stagingData: Staging of colorectal carcinoma

In kappaGold: Agreement of Nominal Scale Raters (with a Gold Standard)

Staging of colorectal carcinoma

Description

Staging of carcinoma is done by different medical professions. Gold standard is the (histo-)pathological rating of a tissue sample but this information typically only becomes available late, after surgery. However prior to surgery the carcinoma is also staged by radiologists in the clinical setting on the basis of MRI scans.

Usage

stagingData

Format

A data frame with 21 observations and 6 variables:

patho

the (histo-)pathological staging (gold standard) with categories I, II or III

rad1

the clinical staging with categories I, II or III by radiologist 1

rad2

the clinical staging with categories I, II or III by radiologist 2

rad3

the clinical staging with categories I, II or III by radiologist 3

rad4

the clinical staging with categories I, II or III by radiologist 4

rad5

the clinical staging with categories I, II or III by radiologist 5

Details

These fictitious data were inspired by the OCUM trial. The simulation uses the following two assumptions: over-staging occurs more frequently than under-staging and an error by two categories is less likely than an error by only one category.

Stages conform to the UICC classification according to the TNM classification. Note that cases in stage IV do not appear in this data set and that the following description of stages is simplified.

1. I Until T2, N0, M0

2. II From T3, N0, M0

3. III Any T, N1/N2, M0

Source

simulated data

References

Kreis, M. E. et al., MRI-Based Use of Neoadjuvant Chemoradiotherapy in Rectal Carcinoma: Surgical Quality and Histopathological Outcome of the OCUM Trial \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1245/s10434-019-07696-y")}

kappaGold documentation built on April 4, 2025, 1:02 a.m.