dat.phq9: Example data set: Patient Health Questionnaire-9 (PHQ-9)...

In metamedian: Meta-Analysis of Medians

Example data set: Patient Health Questionnaire-9 (PHQ-9) scores (processed version)

Description

A data set based on a meta-analysis of Patient Health Questionnaire-9 (PHQ-9) scores (Thombs et al. 2014, Levis et al. 2019). This data set was obtained by performing the following data processing items to dat.phq9_raw. We randomly selected 14 of the primary studies to report S1 summary statistics, 14 to report S2 summary statistics, 15 to report S3 summary statistics, and 15 to report S4 summary statistics. Since some of the mean-based methods require the sample quantiles to be strictly positive and PHQ-9 scores of 0 were observed in some of the primary studies, we added a value of 0.01 to sample quantiles with a value of 0. Additionally, since some of the mean-based methods do not allow for "ties" in the quantiles (e.g., when the minimum value equals the first quartile value), we added a value of 0.25 to the larger quantile in the event of ties.

Usage

dat.phq9

Format

A data frame with 58 rows and 9 columns:

author	first author of the primary study and the year of publication.
n.g1	number of subjects.
min.g1	minimum PHQ-9 score.
q1.g1	first quartile of the PHQ-9 scores.
med.g1	median PHQ-9 score.
q3.g1	third quartile of the PHQ-9 scores.
max.g1	maximum PHQ-9 score.
mean.g1	mean PHQ-9 score.
sd.g1	standard deviation of the PHQ-9 scores.

References

Thombs B.D., Benedetti A., Kloda L.A., et al. (2014). The diagnostic accuracy of the Patient Health Questionnaire-2 (PHQ-2), Patient Health Questionnaire-8 (PHQ-8), and Patient Health Questionnaire-9 (PHQ-9) for detecting major depression: protocol for a systematic review and individual patient data meta-analyses. Systematic Reviews. 3(1):1-16.

Levis B., Benedetti A., Thombs B.D., and the DEPRESsion Screening Data (DEPRESSD) Collaboration. (2019). The diagnostic accuracy of the Patient Health Questionnaire-9 (PHQ-9) for detecting major depression. BMJ. 365:l1476.

McGrath S., Zhao X., Steele R., Thombs B.D., Benedetti A., and the DEPRESsion Screening Data (DEPRESSD) Collaboration. (2020). Estimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis. Statistical Methods in Medical Research. 29(9):2520-2537.

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