anemia: Aplastic anemia clinical trial data.

In mhazard: Nonparametric and Semiparametric Methods for Multivariate Failure Time Data

Aplastic anemia clinical trial data.

Description

Failure time data for 64 patients having severe aplastic anemia. Patients were randomly assigned to receive either cyclosporine plus methotrexate (CSPMTX) or methotrexate alone (MTX) with time from assignment to the diagnosis of stage 2 or greater acute graft versus host disease (A-GVHD) as a key outcome.

Usage

data(anemia)

Format

A data frame with 64 rows and 5 variables:

Treatment:

Treatment group, either cyclosporine and methotrexate (CSPMTX) or methotrexate only (MTX).

Time:

Time in days to severe (stage >=2) acute graft versus host disease, death, or last contact.

LAF:

Patient assigned to laminar air flow isolation room at baseline. LAF = 1 signifies yes, LAF = 0 signifies no.

Age:

Age of patient in years.

Censored:

Boolean for whether or not time to severe A-GVHD is right-censored; i.e., the patient died without severe A-GVHD or was without severe A-GVHD at last contact.

Source

Table 1.1, page 14 of Prentice and Zhao 2019, taken from Table 1.2 on page 3 in The Statistical Analysis of Failure Time Data, Second Edition, by J. D. Kalbfleisch and R. L. Prentice. New York: Wiley and Sons, 2002.

References

Prentice, R., Zhao, S. "The statistical analysis of multivariate failure time data: A marginal modeling approach", CRC Press (2019).

mhazard documentation built on Aug. 17, 2023, 5:12 p.m.