IPDNa: A simulated Individual Patient Data (IPD) meta-analysis with...
In micemd: Multiple Imputation by Chained Equations with Multilevel Data
Description
Usage
Format
Details
Source
References
Examples
Description
This dataset is a simulated version of an IPD meta-analysis consisting of 28 studies focusing on risk factors in acute heart failure (GREAT, 2013). Each study includes a list of patient characteristics and potential risk factors. Each of them is incomplete, leading to sporadically missing values (Resche-Rigon, et al 2013). In addition, some variables have been collected on some studies only, leading to systematically missing values. More details on the original dataset are provided in Audigier et al. (2018). To mimic the real data, a general location model has been fitted on each study (Schafer, 1997). Then, each study has been generated according to the estimated parameters. Finally, missing values have been allocated similarly to the original dataset.
Usage
1
data("IPDNa")
Format
A data frame with 11685 observations on the following 10 variables.
centrea numeric indexing the center where the study is conducted
gendera factor with levels 0 1
bmia numeric vector indicating the body mass index
agea numeric vector indicating the age
sbpa numeric vector indicating the systolic blood pressure
dbpa numeric vector indicating the diastolic blood pressure
hra numeric vector indicating the heart rate
lvefa numeric vector indicating the ventricular ejection fraction
bnpa numeric vector indicating the level of the brain natriuretic peptide biomarker
afiba factor with levels 0 1 indicating the atrial fibrillation
Details
For more details, see Audigier et al. (2018)
Source
GREAT Network (2013). Managing acute heart failure in the ed - case studies
from the acute heart failure academy. http://www.greatnetwork.org
References
Audigier, V., White, I. , Jolani ,S. Debray, T., Quartagno, M., Carpenter, J., van Buuren, S. and Resche-Rigon, M.
Multiple imputation for multilevel data with continuous and binary variables (2018). Statistical Science. <doi:10.1214/18-STS646>.
Resche-Rigon, M., White, I. R., Bartlett, J., Peters, S., Thompson, S., and on behalf of the
PROG-IMT Study Group (2013). Multiple imputation for handling systematically missing
confounders in meta-analysis of individual participant data. Statistics in Medicine,
32(28):48904905. <doi:10.1002/sim.5894>
Schafer, J. L. (1997) Analysis of Incomplete Multivariate Data. Chapman \& Hall, Chapter 9.
Examples
1
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7
Example output
Loading required package: mice
centre gender bmi age sbp
Min. : 1.00 0:6916 Min. : 10.86 Min. : 18.00 Min. : 22.0
1st Qu.:12.00 1:4769 1st Qu.: 23.34 1st Qu.: 60.00 1st Qu.:112.0
Median :16.00 Median : 26.72 Median : 70.00 Median :133.0
Mean :15.24 Mean : 27.31 Mean : 70.46 Mean :135.1
3rd Qu.:21.00 3rd Qu.: 30.58 3rd Qu.: 80.00 3rd Qu.:156.0
Max. :28.00 Max. :116.24 Max. :176.00 Max. :305.0
NA's :2426 NA's :7 NA's :407
dbp hr lvef bnp afib
Min. : 6.00 Min. : 27.0 Min. :0.040 Min. : 0.997 0 :7800
1st Qu.: 66.00 1st Qu.: 72.0 1st Qu.:0.270 1st Qu.: 2.558 1 :3335
Median : 79.00 Median : 86.0 Median :0.360 Median : 2.917 NA's: 550
Mean : 78.59 Mean : 90.5 Mean :0.398 Mean : 2.961
3rd Qu.: 91.00 3rd Qu.:105.0 3rd Qu.:0.480 3rd Qu.: 3.331
Max. :163.00 Max. :284.0 Max. :2.260 Max. :10.123
NA's :423 NA's :167 NA's :8909
IPDNa$centre: 1
centre gender bmi age sbp
Min. :1 0:203 Min. :15.11 Min. : 50.00 Min. : 71.0
1st Qu.:1 1:207 1st Qu.:24.26 1st Qu.: 64.00 1st Qu.:121.0
Median :1 Median :28.07 Median : 72.00 Median :142.0
Mean :1 Mean :28.49 Mean : 72.72 Mean :143.5
3rd Qu.:1 3rd Qu.:31.35 3rd Qu.: 79.00 3rd Qu.:163.0
Max. :1 Max. :48.18 Max. :108.00 Max. :247.0
NA's :148 NA's :1 NA's :4
dbp hr lvef bnp afib
Min. : 16.00 Min. : 30.00 Min. :0.1100 Min. :1.855 0 :323
1st Qu.: 68.00 1st Qu.: 74.00 1st Qu.:0.3200 1st Qu.:2.671 1 : 86
Median : 82.00 Median : 88.00 Median :0.4150 Median :2.934 NA's: 1
Mean : 81.38 Mean : 92.11 Mean :0.4539 Mean :3.008
3rd Qu.: 95.00 3rd Qu.:108.00 3rd Qu.:0.5600 3rd Qu.:3.343
Max. :142.00 Max. :194.00 Max. :1.2300 Max. :4.421
NA's :8 NA's :12 NA's :235
------------------------------------------------------------
IPDNa$centre: 2
centre gender bmi age sbp
Min. :2 0:319 Min. :14.98 Min. : 36.00 Min. : 67.0
1st Qu.:2 1:248 1st Qu.:24.26 1st Qu.: 58.00 1st Qu.:125.8
Median :2 Median :28.08 Median : 68.00 Median :147.0
Mean :2 Mean :29.06 Mean : 70.48 Mean :146.8
3rd Qu.:2 3rd Qu.:33.22 3rd Qu.: 81.00 3rd Qu.:167.0
Max. :2 Max. :53.54 Max. :148.00 Max. :242.0
NA's :105 NA's :11
dbp hr lvef bnp afib
Min. : 29.00 Min. : 35.00 Min. :0.0600 Min. :1.845 0:433
1st Qu.: 66.00 1st Qu.: 68.00 1st Qu.:0.2100 1st Qu.:2.612 1:134
Median : 79.00 Median : 80.00 Median :0.3000 Median :2.908
Mean : 78.68 Mean : 82.29 Mean :0.3489 Mean :2.948
3rd Qu.: 92.00 3rd Qu.: 94.00 3rd Qu.:0.4300 3rd Qu.:3.248
Max. :136.00 Max. :229.00 Max. :1.6900 Max. :5.053
NA's :17 NA's :6 NA's :57
------------------------------------------------------------
IPDNa$centre: 3
centre gender bmi age sbp
Min. :3 0:150 Min. :16.42 Min. : 43.00 Min. : 70.0
1st Qu.:3 1: 60 1st Qu.:24.94 1st Qu.: 61.25 1st Qu.:109.0
Median :3 Median :27.76 Median : 69.00 Median :130.0
Mean :3 Mean :28.27 Mean : 71.95 Mean :129.2
3rd Qu.:3 3rd Qu.:31.58 3rd Qu.: 80.75 3rd Qu.:147.5
Max. :3 Max. :42.85 Max. :134.00 Max. :221.0
NA's :90 NA's :3
dbp hr lvef bnp afib
Min. : 42.00 Min. : 44.00 Min. :0.0800 Min. :2.036 0 : 0
1st Qu.: 68.00 1st Qu.: 71.00 1st Qu.:0.2400 1st Qu.:2.860 1 : 0
Median : 76.00 Median : 83.00 Median :0.3300 Median :3.276 NA's:210
Mean : 75.41 Mean : 85.55 Mean :0.3670 Mean :3.325
3rd Qu.: 84.00 3rd Qu.: 99.00 3rd Qu.:0.4375 3rd Qu.:3.713
Max. :103.00 Max. :160.00 Max. :1.1600 Max. :5.258
NA's :4 NA's :3
------------------------------------------------------------
IPDNa$centre: 4
centre gender bmi age sbp
Min. :4 0:232 Min. :14.39 Min. : 41.00 Min. : 57.0
1st Qu.:4 1:143 1st Qu.:23.18 1st Qu.: 66.00 1st Qu.:122.2
Median :4 Median :25.78 Median : 74.00 Median :141.0
Mean :4 Mean :26.72 Mean : 73.83 Mean :141.7
3rd Qu.:4 3rd Qu.:29.69 3rd Qu.: 81.00 3rd Qu.:159.0
Max. :4 Max. :52.27 Max. :106.00 Max. :264.0
NA's :9 NA's :5
dbp hr lvef bnp afib
Min. : 29.00 Min. : 40.00 Min. :0.1000 Min. :1.658 0 :135
1st Qu.: 76.00 1st Qu.: 76.00 1st Qu.:0.2900 1st Qu.:2.636 1 : 84
Median : 88.50 Median : 90.00 Median :0.3900 Median :2.905 NA's:156
Mean : 87.65 Mean : 94.49 Mean :0.4193 Mean :2.938
3rd Qu.:100.00 3rd Qu.:109.00 3rd Qu.:0.5000 3rd Qu.:3.241
Max. :163.00 Max. :202.00 Max. :1.3600 Max. :4.771
NA's :5 NA's :9 NA's :15
------------------------------------------------------------
IPDNa$centre: 5
centre gender bmi age sbp
Min. :5 0:59 Min. :17.74 Min. : 41.00 Min. : 86.0
1st Qu.:5 1:48 1st Qu.:26.01 1st Qu.: 62.00 1st Qu.:134.5
Median :5 Median :27.85 Median : 70.00 Median :153.0
Mean :5 Mean :28.71 Mean : 74.23 Mean :153.3
3rd Qu.:5 3rd Qu.:31.70 3rd Qu.: 82.00 3rd Qu.:162.5
Max. :5 Max. :39.11 Max. :176.00 Max. :246.0
NA's :1
dbp hr lvef bnp afib
Min. : 45.00 Min. : 45.0 Min. :0.2100 Min. : NA 0:48
1st Qu.: 74.00 1st Qu.: 83.0 1st Qu.:0.3600 1st Qu.: NA 1:59
Median : 87.00 Median :101.0 Median :0.4700 Median : NA
Mean : 86.73 Mean :105.0 Mean :0.4848 Mean :NaN
3rd Qu.: 99.50 3rd Qu.:124.5 3rd Qu.:0.5800 3rd Qu.: NA
Max. :131.00 Max. :198.0 Max. :1.2000 Max. : NA
NA's :107
------------------------------------------------------------
IPDNa$centre: 6
centre gender bmi age sbp dbp
Min. :6 0:150 Min. : NA Min. : 44.00 Min. : NA Min. : NA
1st Qu.:6 1:117 1st Qu.: NA 1st Qu.: 66.00 1st Qu.: NA 1st Qu.: NA
Median :6 Median : NA Median : 72.00 Median : NA Median : NA
Mean :6 Mean :NaN Mean : 74.09 Mean :NaN Mean :NaN
3rd Qu.:6 3rd Qu.: NA 3rd Qu.: 82.00 3rd Qu.: NA 3rd Qu.: NA
Max. :6 Max. : NA Max. :125.00 Max. : NA Max. : NA
NA's :267 NA's :267 NA's :267
hr lvef bnp afib
Min. : 35.00 Min. :0.1400 Min. : NA 0:160
1st Qu.: 74.00 1st Qu.:0.2900 1st Qu.: NA 1:107
Median : 93.00 Median :0.3700 Median : NA
Mean : 97.37 Mean :0.4131 Mean :NaN
3rd Qu.:116.00 3rd Qu.:0.5100 3rd Qu.: NA
Max. :284.00 Max. :0.9300 Max. : NA
NA's :1 NA's :267
------------------------------------------------------------
IPDNa$centre: 7
centre gender bmi age sbp
Min. :7 0: 97 Min. :16.66 Min. : 36.0 Min. : 55.0
1st Qu.:7 1:106 1st Qu.:23.11 1st Qu.: 60.0 1st Qu.:120.8
Median :7 Median :27.01 Median : 70.0 Median :138.0
Mean :7 Mean :27.33 Mean : 71.4 Mean :140.6
3rd Qu.:7 3rd Qu.:30.79 3rd Qu.: 81.0 3rd Qu.:159.2
Max. :7 Max. :42.73 Max. :125.0 Max. :238.0
NA's :1 NA's :3
dbp hr lvef bnp afib
Min. : 25.00 Min. : 40.00 Min. :0.1500 Min. :1.165 0:127
1st Qu.: 64.00 1st Qu.: 66.00 1st Qu.:0.3350 1st Qu.:1.972 1: 76
Median : 78.00 Median : 80.00 Median :0.4400 Median :2.387
Mean : 76.78 Mean : 85.27 Mean :0.4937 Mean :2.463
3rd Qu.: 88.50 3rd Qu.: 98.25 3rd Qu.:0.6000 3rd Qu.:2.825
Max. :129.00 Max. :207.00 Max. :1.4000 Max. :6.454
NA's :4 NA's :3 NA's :1
------------------------------------------------------------
IPDNa$centre: 8
centre gender bmi age sbp
Min. :8 0:235 Min. :17.05 Min. : 37.0 Min. : 50
1st Qu.:8 1:119 1st Qu.:23.41 1st Qu.: 58.0 1st Qu.:106
Median :8 Median :27.21 Median : 67.0 Median :125
Mean :8 Mean :27.43 Mean : 70.1 Mean :129
3rd Qu.:8 3rd Qu.:30.76 3rd Qu.: 80.0 3rd Qu.:151
Max. :8 Max. :47.71 Max. :153.0 Max. :233
NA's :157 NA's :5 NA's :57
dbp hr lvef bnp afib
Min. : 6.00 Min. : 39.00 Min. :0.0900 Min. :2.168 0 :149
1st Qu.: 62.75 1st Qu.: 69.00 1st Qu.:0.2500 1st Qu.:2.756 1 :127
Median : 75.00 Median : 85.00 Median :0.3400 Median :3.080 NA's: 78
Mean : 76.04 Mean : 86.81 Mean :0.3775 Mean :3.099
3rd Qu.: 89.00 3rd Qu.:100.00 3rd Qu.:0.4675 3rd Qu.:3.407
Max. :129.00 Max. :180.00 Max. :1.2500 Max. :4.391
NA's :58 NA's :67 NA's :44
------------------------------------------------------------
IPDNa$centre: 9
centre gender bmi age sbp
Min. :9 0:126 Min. :16.79 Min. : 43.0 Min. : 42.0
1st Qu.:9 1: 11 1st Qu.:23.17 1st Qu.: 61.0 1st Qu.:108.0
Median :9 Median :25.57 Median : 72.0 Median :131.0
Mean :9 Mean :26.14 Mean : 73.3 Mean :134.9
3rd Qu.:9 3rd Qu.:28.80 3rd Qu.: 83.0 3rd Qu.:155.0
Max. :9 Max. :38.70 Max. :115.0 Max. :305.0
NA's :1
dbp hr lvef bnp afib
Min. : 19.00 Min. : 47.00 Min. :0.1500 Min. :1.958 0:69
1st Qu.: 64.00 1st Qu.: 82.00 1st Qu.:0.3100 1st Qu.:2.630 1:68
Median : 79.00 Median : 94.00 Median :0.3700 Median :2.888
Mean : 77.86 Mean : 99.04 Mean :0.3797 Mean :2.927
3rd Qu.: 91.00 3rd Qu.:116.00 3rd Qu.:0.4500 3rd Qu.:3.187
Max. :125.00 Max. :188.00 Max. :0.8000 Max. :4.099
------------------------------------------------------------
IPDNa$centre: 10
centre gender bmi age sbp
Min. :10 0:25 Min. : NA Min. : 29.00 Min. : 50.0
1st Qu.:10 1:23 1st Qu.: NA 1st Qu.: 39.00 1st Qu.:112.8
Median :10 Median : NA Median : 54.00 Median :142.5
Mean :10 Mean :NaN Mean : 61.42 Mean :147.5
3rd Qu.:10 3rd Qu.: NA 3rd Qu.: 71.50 3rd Qu.:181.2
Max. :10 Max. : NA Max. :154.00 Max. :269.0
NA's :48
dbp hr lvef bnp afib
Min. : 39.00 Min. : 60.0 Min. :0.2100 Min. : NA 0:36
1st Qu.: 72.00 1st Qu.: 89.5 1st Qu.:0.3150 1st Qu.: NA 1:12
Median : 85.00 Median : 99.0 Median :0.5050 Median : NA
Mean : 84.69 Mean :105.0 Mean :0.5773 Mean :NaN
3rd Qu.:100.00 3rd Qu.:117.8 3rd Qu.:0.6575 3rd Qu.: NA
Max. :131.00 Max. :175.0 Max. :2.2600 Max. : NA
NA's :2 NA's :48
------------------------------------------------------------
IPDNa$centre: 11
centre gender bmi age sbp
Min. :11 0:140 Min. :16.79 Min. : 39.00 Min. : 54.0
1st Qu.:11 1: 68 1st Qu.:24.16 1st Qu.: 55.00 1st Qu.:101.0
Median :11 Median :27.66 Median : 65.00 Median :118.5
Mean :11 Mean :27.25 Mean : 67.02 Mean :123.3
3rd Qu.:11 3rd Qu.:30.16 3rd Qu.: 76.00 3rd Qu.:142.2
Max. :11 Max. :38.00 Max. :162.00 Max. :224.0
NA's :49
dbp hr lvef bnp afib
Min. : 32.0 Min. : 32.0 Min. :0.0900 Min. : NA 0:160
1st Qu.: 61.0 1st Qu.: 71.0 1st Qu.:0.2500 1st Qu.: NA 1: 48
Median : 74.0 Median : 86.0 Median :0.3500 Median : NA
Mean : 74.4 Mean : 87.2 Mean :0.3715 Mean :NaN
3rd Qu.: 88.0 3rd Qu.: 99.0 3rd Qu.:0.4400 3rd Qu.: NA
Max. :114.0 Max. :159.0 Max. :1.4400 Max. : NA
NA's :1 NA's :208
------------------------------------------------------------
IPDNa$centre: 12
centre gender bmi age sbp
Min. :12 0:424 Min. :15.52 Min. : 41.00 Min. : 47.0
1st Qu.:12 1:198 1st Qu.:23.95 1st Qu.: 61.00 1st Qu.:107.0
Median :12 Median :27.12 Median : 69.00 Median :126.0
Mean :12 Mean :27.50 Mean : 71.05 Mean :127.1
3rd Qu.:12 3rd Qu.:30.49 3rd Qu.: 79.00 3rd Qu.:147.0
Max. :12 Max. :47.07 Max. :141.00 Max. :261.0
NA's :167 NA's :3
dbp hr lvef bnp afib
Min. : 21.00 Min. : 40.00 Min. :0.1300 Min. : NA 0:346
1st Qu.: 65.00 1st Qu.: 73.00 1st Qu.:0.2600 1st Qu.: NA 1:276
Median : 76.00 Median : 85.00 Median :0.3500 Median : NA
Mean : 75.08 Mean : 88.98 Mean :0.3741 Mean :NaN
3rd Qu.: 86.00 3rd Qu.:100.00 3rd Qu.:0.4500 3rd Qu.: NA
Max. :130.00 Max. :166.00 Max. :1.1300 Max. : NA
NA's :3 NA's :9 NA's :622
------------------------------------------------------------
IPDNa$centre: 13
centre gender bmi age sbp
Min. :13 0:36 Min. :17.37 Min. :26.00 Min. : 76.0
1st Qu.:13 1:42 1st Qu.:22.69 1st Qu.:45.00 1st Qu.:103.0
Median :13 Median :25.90 Median :50.50 Median :113.0
Mean :13 Mean :27.79 Mean :52.58 Mean :115.5
3rd Qu.:13 3rd Qu.:32.14 3rd Qu.:57.50 3rd Qu.:126.2
Max. :13 Max. :48.77 Max. :96.00 Max. :161.0
NA's :47
dbp hr lvef bnp afib
Min. : 42.00 Min. : 50.00 Min. :0.1100 Min. : NA 0 : 0
1st Qu.: 63.00 1st Qu.: 70.50 1st Qu.:0.2025 1st Qu.: NA 1 : 0
Median : 70.50 Median : 82.50 Median :0.2550 Median : NA NA's:78
Mean : 73.09 Mean : 84.69 Mean :0.2728 Mean :NaN
3rd Qu.: 82.00 3rd Qu.: 97.75 3rd Qu.:0.3300 3rd Qu.: NA
Max. :108.00 Max. :156.00 Max. :0.6000 Max. : NA
NA's :78
------------------------------------------------------------
IPDNa$centre: 14
centre gender bmi age sbp
Min. :14 0:333 Min. :16.49 Min. : 53.0 Min. : 59.0
1st Qu.:14 1:337 1st Qu.:23.66 1st Qu.: 71.0 1st Qu.:122.0
Median :14 Median :27.04 Median : 77.0 Median :141.0
Mean :14 Mean :27.43 Mean : 78.1 Mean :142.1
3rd Qu.:14 3rd Qu.:30.28 3rd Qu.: 85.0 3rd Qu.:160.0
Max. :14 Max. :45.61 Max. :111.0 Max. :240.0
NA's :514 NA's :1 NA's :6
dbp hr lvef bnp afib
Min. : 19.00 Min. : 40.00 Min. :0.1500 Min. : NA 0 :302
1st Qu.: 68.00 1st Qu.: 70.00 1st Qu.:0.3500 1st Qu.: NA 1 :367
Median : 80.00 Median : 83.00 Median :0.4600 Median : NA NA's: 1
Mean : 79.28 Mean : 86.27 Mean :0.4789 Mean :NaN
3rd Qu.: 91.00 3rd Qu.: 99.75 3rd Qu.:0.5800 3rd Qu.: NA
Max. :126.00 Max. :174.00 Max. :1.2200 Max. : NA
NA's :6 NA's :12 NA's :670
------------------------------------------------------------
IPDNa$centre: 15
centre gender bmi age sbp
Min. :15 0:490 Min. :13.88 Min. : 29.00 Min. : 57.0
1st Qu.:15 1:510 1st Qu.:20.43 1st Qu.: 57.00 1st Qu.:111.0
Median :15 Median :22.62 Median : 67.00 Median :130.0
Mean :15 Mean :22.96 Mean : 68.92 Mean :131.4
3rd Qu.:15 3rd Qu.:25.20 3rd Qu.: 78.00 3rd Qu.:151.2
Max. :15 Max. :36.33 Max. :152.00 Max. :230.0
NA's :130 NA's :16
dbp hr lvef bnp afib
Min. : 18.00 Min. : 37.00 Min. :0.1000 Min. :1.524 0 :803
1st Qu.: 65.00 1st Qu.: 73.00 1st Qu.:0.2600 1st Qu.:2.325 1 :194
Median : 79.00 Median : 89.00 Median :0.3500 Median :2.803 NA's: 3
Mean : 78.53 Mean : 94.07 Mean :0.3759 Mean :2.904
3rd Qu.: 91.00 3rd Qu.:111.00 3rd Qu.:0.4500 3rd Qu.:3.405
Max. :146.00 Max. :249.00 Max. :1.6900 Max. :5.299
NA's :17 NA's :20 NA's :817
------------------------------------------------------------
IPDNa$centre: 16
centre gender bmi age sbp
Min. :16 0:798 Min. :12.48 Min. : 18.00 Min. : 56.0
1st Qu.:16 1:295 1st Qu.:21.02 1st Qu.: 42.00 1st Qu.:103.0
Median :16 Median :23.41 Median : 53.00 Median :117.0
Mean :16 Mean :23.87 Mean : 56.91 Mean :117.5
3rd Qu.:16 3rd Qu.:26.28 3rd Qu.: 67.00 3rd Qu.:131.0
Max. :16 Max. :41.99 Max. :147.00 Max. :185.0
dbp hr lvef bnp afib
Min. : 33.00 Min. : 40.00 Min. :0.1100 Min. : NA 0:932
1st Qu.: 61.00 1st Qu.: 68.00 1st Qu.:0.3000 1st Qu.: NA 1:161
Median : 70.00 Median : 78.00 Median :0.3900 Median : NA
Mean : 70.23 Mean : 80.13 Mean :0.4146 Mean :NaN
3rd Qu.: 79.00 3rd Qu.: 91.00 3rd Qu.:0.5000 3rd Qu.: NA
Max. :110.00 Max. :156.00 Max. :1.2900 Max. : NA
NA's :1093
------------------------------------------------------------
IPDNa$centre: 17
centre gender bmi age sbp
Min. :17 0:9 Min. : 10.86 Min. : 56.00 Min. : 86.0
1st Qu.:17 1:9 1st Qu.: 26.96 1st Qu.: 59.75 1st Qu.:151.2
Median :17 Median : 38.58 Median : 69.00 Median :170.5
Mean :17 Mean : 45.08 Mean : 71.11 Mean :166.8
3rd Qu.:17 3rd Qu.: 53.67 3rd Qu.: 74.50 3rd Qu.:195.5
Max. :17 Max. :116.24 Max. :108.00 Max. :227.0
NA's :1
dbp hr lvef bnp afib
Min. : 47.00 Min. : 27.00 Min. :0.1300 Min. : 0.9971 0:9
1st Qu.: 70.50 1st Qu.: 75.75 1st Qu.:0.3425 1st Qu.: 1.8052 1:9
Median : 88.50 Median : 91.50 Median :0.5100 Median : 2.6966
Mean : 88.33 Mean : 96.67 Mean :0.6950 Mean : 3.2260
3rd Qu.:107.75 3rd Qu.:104.00 3rd Qu.:0.8150 3rd Qu.: 3.4763
Max. :120.00 Max. :216.00 Max. :1.8800 Max. :10.1229
NA's :4
------------------------------------------------------------
IPDNa$centre: 18
centre gender bmi age sbp
Min. :18 0:1103 Min. :15.56 Min. : 35.00 Min. : 22.0
1st Qu.:18 1: 731 1st Qu.:24.91 1st Qu.: 61.00 1st Qu.:110.0
Median :18 Median :28.10 Median : 70.00 Median :135.0
Mean :18 Mean :28.52 Mean : 71.07 Mean :136.3
3rd Qu.:18 3rd Qu.:31.74 3rd Qu.: 80.00 3rd Qu.:160.0
Max. :18 Max. :49.80 Max. :130.00 Max. :278.0
NA's :357 NA's :11
dbp hr lvef bnp afib
Min. : 14.00 Min. : 29 Min. :0.1100 Min. :1.688 0 :1392
1st Qu.: 66.00 1st Qu.: 72 1st Qu.:0.2800 1st Qu.:2.420 1 : 435
Median : 79.00 Median : 88 Median :0.3700 Median :2.812 NA's: 7
Mean : 79.38 Mean : 93 Mean :0.4032 Mean :2.790
3rd Qu.: 93.00 3rd Qu.:109 3rd Qu.:0.4900 3rd Qu.:3.109
Max. :152.00 Max. :251 Max. :1.5200 Max. :4.365
NA's :11 NA's :6 NA's :1695
------------------------------------------------------------
IPDNa$centre: 19
centre gender bmi age sbp
Min. :19 0:162 Min. :15.40 Min. : 42.00 Min. : 61.0
1st Qu.:19 1:196 1st Qu.:24.49 1st Qu.: 65.00 1st Qu.:118.0
Median :19 Median :27.38 Median : 72.00 Median :140.0
Mean :19 Mean :28.10 Mean : 73.33 Mean :141.4
3rd Qu.:19 3rd Qu.:31.52 3rd Qu.: 80.00 3rd Qu.:163.0
Max. :19 Max. :50.25 Max. :119.00 Max. :244.0
NA's :26
dbp hr lvef bnp afib
Min. : 37.00 Min. : 29.00 Min. :0.1100 Min. :1.550 0:248
1st Qu.: 71.00 1st Qu.: 74.00 1st Qu.:0.2700 1st Qu.:2.180 1:110
Median : 82.00 Median : 91.50 Median :0.3600 Median :2.500
Mean : 81.68 Mean : 97.14 Mean :0.3812 Mean :2.376
3rd Qu.: 93.00 3rd Qu.:116.00 3rd Qu.:0.4600 3rd Qu.:2.696
Max. :133.00 Max. :250.00 Max. :0.9800 Max. :2.954
NA's :354
------------------------------------------------------------
IPDNa$centre: 20
centre gender bmi age sbp
Min. :20 0:25 Min. :21.66 Min. : 54.00 Min. : 72.0
1st Qu.:20 1:29 1st Qu.:26.31 1st Qu.: 69.00 1st Qu.:125.0
Median :20 Median :29.90 Median : 76.00 Median :157.0
Mean :20 Mean :29.46 Mean : 76.57 Mean :151.8
3rd Qu.:20 3rd Qu.:32.37 3rd Qu.: 83.50 3rd Qu.:179.0
Max. :20 Max. :42.69 Max. :101.00 Max. :223.0
NA's :3 NA's :1
dbp hr lvef bnp afib
Min. : 55.00 Min. : 56.00 Min. :0.1200 Min. : NA 0 :23
1st Qu.: 74.00 1st Qu.: 81.00 1st Qu.:0.2125 1st Qu.: NA 1 :30
Median : 89.00 Median : 91.00 Median :0.3400 Median : NA NA's: 1
Mean : 85.43 Mean : 91.91 Mean :0.3746 Mean :NaN
3rd Qu.: 95.00 3rd Qu.:102.00 3rd Qu.:0.4775 3rd Qu.: NA
Max. :120.00 Max. :148.00 Max. :1.2400 Max. : NA
NA's :1 NA's :1 NA's :54
------------------------------------------------------------
IPDNa$centre: 21
centre gender bmi age sbp
Min. :21 0:380 Min. :15.52 Min. : 33.00 Min. : 39.0
1st Qu.:21 1:208 1st Qu.:23.80 1st Qu.: 62.75 1st Qu.:107.0
Median :21 Median :27.01 Median : 71.00 Median :128.0
Mean :21 Mean :27.86 Mean : 72.63 Mean :131.8
3rd Qu.:21 3rd Qu.:31.03 3rd Qu.: 80.00 3rd Qu.:155.0
Max. :21 Max. :47.76 Max. :148.00 Max. :246.0
NA's :59 NA's :2
dbp hr lvef bnp afib
Min. : 17.00 Min. : 39.00 Min. :0.0400 Min. :1.943 0 :423
1st Qu.: 65.00 1st Qu.: 73.00 1st Qu.:0.2000 1st Qu.:2.236 1 :164
Median : 78.00 Median : 87.00 Median :0.2900 Median :2.520 NA's: 1
Mean : 77.45 Mean : 89.99 Mean :0.3371 Mean :2.545
3rd Qu.: 89.00 3rd Qu.:103.00 3rd Qu.:0.4100 3rd Qu.:2.794
Max. :122.00 Max. :228.00 Max. :1.5000 Max. :3.429
NA's :2 NA's :571
------------------------------------------------------------
IPDNa$centre: 22
centre gender bmi age sbp
Min. :22 0:307 Min. :14.94 Min. : 44.00 Min. : 65.0
1st Qu.:22 1:344 1st Qu.:24.79 1st Qu.: 67.00 1st Qu.:121.0
Median :22 Median :28.00 Median : 74.00 Median :139.0
Mean :22 Mean :28.70 Mean : 75.55 Mean :141.1
3rd Qu.:22 3rd Qu.:32.22 3rd Qu.: 83.00 3rd Qu.:161.0
Max. :22 Max. :45.96 Max. :123.00 Max. :250.0
NA's :156 NA's :14
dbp hr lvef bnp afib
Min. : 36.00 Min. : 31.00 Min. :0.1300 Min. :1.611 0 :406
1st Qu.: 72.00 1st Qu.: 79.50 1st Qu.:0.3000 1st Qu.:2.495 1 :234
Median : 82.00 Median : 94.00 Median :0.3900 Median :2.825 NA's: 11
Mean : 82.11 Mean : 97.27 Mean :0.4178 Mean :2.905
3rd Qu.: 92.00 3rd Qu.:112.00 3rd Qu.:0.5000 3rd Qu.:3.290
Max. :139.00 Max. :227.00 Max. :1.1600 Max. :4.899
NA's :15 NA's :12 NA's :476
------------------------------------------------------------
IPDNa$centre: 23
centre gender bmi age sbp
Min. :23 0:251 Min. :19.35 Min. : 46.00 Min. : 57.0
1st Qu.:23 1:204 1st Qu.:26.83 1st Qu.: 66.00 1st Qu.:125.0
Median :23 Median :30.06 Median : 74.00 Median :145.0
Mean :23 Mean :30.77 Mean : 74.76 Mean :146.3
3rd Qu.:23 3rd Qu.:33.81 3rd Qu.: 82.00 3rd Qu.:166.0
Max. :23 Max. :53.67 Max. :109.00 Max. :242.0
NA's :7
dbp hr lvef bnp afib
Min. : 25.00 Min. : 41.00 Min. :0.0900 Min. :2.693 0 :240
1st Qu.: 74.00 1st Qu.: 76.00 1st Qu.:0.2600 1st Qu.:3.460 1 :214
Median : 85.00 Median : 90.00 Median :0.3300 Median :3.753 NA's: 1
Mean : 84.86 Mean : 95.97 Mean :0.3553 Mean :3.819
3rd Qu.: 96.00 3rd Qu.:110.00 3rd Qu.:0.4200 3rd Qu.:4.271
Max. :137.00 Max. :202.00 Max. :0.8900 Max. :5.389
NA's :1 NA's :393
------------------------------------------------------------
IPDNa$centre: 24
centre gender bmi age sbp
Min. :24 0:206 Min. :16.31 Min. : 38.00 Min. : 43.0
1st Qu.:24 1: 88 1st Qu.:23.99 1st Qu.: 56.00 1st Qu.:110.0
Median :24 Median :26.99 Median : 66.00 Median :136.0
Mean :24 Mean :27.53 Mean : 67.32 Mean :135.5
3rd Qu.:24 3rd Qu.:30.58 3rd Qu.: 77.00 3rd Qu.:159.0
Max. :24 Max. :44.42 Max. :128.00 Max. :257.0
NA's :13 NA's :1
dbp hr lvef bnp afib
Min. : 16.00 Min. : 37.00 Min. :0.1100 Min. :1.949 0:234
1st Qu.: 61.00 1st Qu.: 73.00 1st Qu.:0.2300 1st Qu.:2.470 1: 60
Median : 76.00 Median : 88.00 Median :0.3000 Median :2.911
Mean : 74.45 Mean : 93.09 Mean :0.3323 Mean :2.941
3rd Qu.: 90.00 3rd Qu.:110.00 3rd Qu.:0.4000 3rd Qu.:3.381
Max. :117.00 Max. :192.00 Max. :1.0400 Max. :4.187
NA's :1 NA's :1 NA's :237
------------------------------------------------------------
IPDNa$centre: 25
centre gender bmi age sbp
Min. :25 0:286 Min. :17.16 Min. : 38.00 Min. : 51.0
1st Qu.:25 1:111 1st Qu.:25.84 1st Qu.: 58.00 1st Qu.:112.0
Median :25 Median :28.94 Median : 66.00 Median :130.0
Mean :25 Mean :28.92 Mean : 68.37 Mean :132.9
3rd Qu.:25 3rd Qu.:31.84 3rd Qu.: 77.00 3rd Qu.:155.0
Max. :25 Max. :45.52 Max. :126.00 Max. :223.0
NA's :5 NA's :2
dbp hr lvef bnp afib
Min. : 26.00 Min. : 44.00 Min. :0.1000 Min. : NA 0 :325
1st Qu.: 66.00 1st Qu.: 74.00 1st Qu.:0.2700 1st Qu.: NA 1 : 70
Median : 80.00 Median : 87.00 Median :0.3400 Median : NA NA's: 2
Mean : 78.62 Mean : 90.36 Mean :0.3727 Mean :NaN
3rd Qu.: 92.00 3rd Qu.:105.00 3rd Qu.:0.4500 3rd Qu.: NA
Max. :138.00 Max. :185.00 Max. :1.1400 Max. : NA
NA's :2 NA's :2 NA's :397
------------------------------------------------------------
IPDNa$centre: 26
centre gender bmi age sbp
Min. :26 0:182 Min. :17.16 Min. : 35.0 Min. : 62.0
1st Qu.:26 1:113 1st Qu.:24.31 1st Qu.: 59.0 1st Qu.:110.0
Median :26 Median :27.35 Median : 69.0 Median :131.0
Mean :26 Mean :27.99 Mean : 70.9 Mean :132.1
3rd Qu.:26 3rd Qu.:31.04 3rd Qu.: 80.0 3rd Qu.:151.5
Max. :26 Max. :46.67 Max. :140.0 Max. :215.0
NA's :33
dbp hr lvef bnp afib
Min. : 32.00 Min. : 32.0 Min. :0.1400 Min. :2.060 0:214
1st Qu.: 66.00 1st Qu.: 66.5 1st Qu.:0.2900 1st Qu.:2.679 1: 81
Median : 77.00 Median : 82.0 Median :0.4000 Median :3.029
Mean : 77.74 Mean : 88.7 Mean :0.4344 Mean :3.027
3rd Qu.: 90.00 3rd Qu.:108.5 3rd Qu.:0.5300 3rd Qu.:3.274
Max. :125.00 Max. :215.0 Max. :1.1600 Max. :4.543
NA's :194
------------------------------------------------------------
IPDNa$centre: 27
centre gender bmi age sbp
Min. :27 0:143 Min. :18.16 Min. : 43.00 Min. : 54.0
1st Qu.:27 1:160 1st Qu.:25.60 1st Qu.: 65.50 1st Qu.:122.0
Median :27 Median :28.26 Median : 74.00 Median :142.0
Mean :27 Mean :28.98 Mean : 74.56 Mean :145.9
3rd Qu.:27 3rd Qu.:31.53 3rd Qu.: 84.00 3rd Qu.:170.0
Max. :27 Max. :53.58 Max. :117.00 Max. :272.0
NA's :32 NA's :1
dbp hr lvef bnp afib
Min. : 36.00 Min. : 31.00 Min. :0.150 Min. :1.791 0:218
1st Qu.: 71.00 1st Qu.: 67.00 1st Qu.:0.280 1st Qu.:2.523 1: 85
Median : 84.00 Median : 84.00 Median :0.380 Median :3.128
Mean : 84.69 Mean : 88.18 Mean :0.405 Mean :3.071
3rd Qu.: 97.00 3rd Qu.:105.00 3rd Qu.:0.500 3rd Qu.:3.447
Max. :150.00 Max. :207.00 Max. :0.940 Max. :5.280
NA's :1 NA's :238
------------------------------------------------------------
IPDNa$centre: 28
centre gender bmi age sbp
Min. :28 0:45 Min. :19.67 Min. : 47.00 Min. : 85.0
1st Qu.:28 1:44 1st Qu.:24.63 1st Qu.: 66.00 1st Qu.:121.0
Median :28 Median :28.07 Median : 75.00 Median :132.0
Mean :28 Mean :28.87 Mean : 75.73 Mean :136.5
3rd Qu.:28 3rd Qu.:33.07 3rd Qu.: 83.00 3rd Qu.:149.0
Max. :28 Max. :41.96 Max. :129.00 Max. :222.0
dbp hr lvef bnp afib
Min. : 56.00 Min. : 41.00 Min. :0.1500 Min. :1.385 0:45
1st Qu.: 72.00 1st Qu.: 73.00 1st Qu.:0.2700 1st Qu.:2.196 1:44
Median : 85.00 Median : 87.00 Median :0.3800 Median :2.423
Mean : 84.55 Mean : 90.34 Mean :0.4274 Mean :2.528
3rd Qu.: 95.00 3rd Qu.:107.00 3rd Qu.:0.5000 3rd Qu.:2.818
Max. :130.00 Max. :174.00 Max. :1.7300 Max. :3.893
NA's :34
micemd documentation built on Oct. 15, 2021, 5:10 p.m.
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Description Usage Format Details Source References Examples
Description
This dataset is a simulated version of an IPD meta-analysis consisting of 28 studies focusing on risk factors in acute heart failure (GREAT, 2013). Each study includes a list of patient characteristics and potential risk factors. Each of them is incomplete, leading to sporadically missing values (Resche-Rigon, et al 2013). In addition, some variables have been collected on some studies only, leading to systematically missing values. More details on the original dataset are provided in Audigier et al. (2018). To mimic the real data, a general location model has been fitted on each study (Schafer, 1997). Then, each study has been generated according to the estimated parameters. Finally, missing values have been allocated similarly to the original dataset.
Usage
1 | data("IPDNa")
|
Format
A data frame with 11685 observations on the following 10 variables.
centrea numeric indexing the center where the study is conducted
gendera factor with levels
01bmia numeric vector indicating the body mass index
agea numeric vector indicating the age
sbpa numeric vector indicating the systolic blood pressure
dbpa numeric vector indicating the diastolic blood pressure
hra numeric vector indicating the heart rate
lvefa numeric vector indicating the ventricular ejection fraction
bnpa numeric vector indicating the level of the brain natriuretic peptide biomarker
afiba factor with levels
01indicating the atrial fibrillation
Details
For more details, see Audigier et al. (2018)
Source
GREAT Network (2013). Managing acute heart failure in the ed - case studies from the acute heart failure academy. http://www.greatnetwork.org
References
Audigier, V., White, I. , Jolani ,S. Debray, T., Quartagno, M., Carpenter, J., van Buuren, S. and Resche-Rigon, M. Multiple imputation for multilevel data with continuous and binary variables (2018). Statistical Science. <doi:10.1214/18-STS646>.
Resche-Rigon, M., White, I. R., Bartlett, J., Peters, S., Thompson, S., and on behalf of the PROG-IMT Study Group (2013). Multiple imputation for handling systematically missing confounders in meta-analysis of individual participant data. Statistics in Medicine, 32(28):48904905. <doi:10.1002/sim.5894>
Schafer, J. L. (1997) Analysis of Incomplete Multivariate Data. Chapman \& Hall, Chapter 9.
Examples
1 2 3 4 5 6 7 |
Example output
Loading required package: mice
centre gender bmi age sbp
Min. : 1.00 0:6916 Min. : 10.86 Min. : 18.00 Min. : 22.0
1st Qu.:12.00 1:4769 1st Qu.: 23.34 1st Qu.: 60.00 1st Qu.:112.0
Median :16.00 Median : 26.72 Median : 70.00 Median :133.0
Mean :15.24 Mean : 27.31 Mean : 70.46 Mean :135.1
3rd Qu.:21.00 3rd Qu.: 30.58 3rd Qu.: 80.00 3rd Qu.:156.0
Max. :28.00 Max. :116.24 Max. :176.00 Max. :305.0
NA's :2426 NA's :7 NA's :407
dbp hr lvef bnp afib
Min. : 6.00 Min. : 27.0 Min. :0.040 Min. : 0.997 0 :7800
1st Qu.: 66.00 1st Qu.: 72.0 1st Qu.:0.270 1st Qu.: 2.558 1 :3335
Median : 79.00 Median : 86.0 Median :0.360 Median : 2.917 NA's: 550
Mean : 78.59 Mean : 90.5 Mean :0.398 Mean : 2.961
3rd Qu.: 91.00 3rd Qu.:105.0 3rd Qu.:0.480 3rd Qu.: 3.331
Max. :163.00 Max. :284.0 Max. :2.260 Max. :10.123
NA's :423 NA's :167 NA's :8909
IPDNa$centre: 1
centre gender bmi age sbp
Min. :1 0:203 Min. :15.11 Min. : 50.00 Min. : 71.0
1st Qu.:1 1:207 1st Qu.:24.26 1st Qu.: 64.00 1st Qu.:121.0
Median :1 Median :28.07 Median : 72.00 Median :142.0
Mean :1 Mean :28.49 Mean : 72.72 Mean :143.5
3rd Qu.:1 3rd Qu.:31.35 3rd Qu.: 79.00 3rd Qu.:163.0
Max. :1 Max. :48.18 Max. :108.00 Max. :247.0
NA's :148 NA's :1 NA's :4
dbp hr lvef bnp afib
Min. : 16.00 Min. : 30.00 Min. :0.1100 Min. :1.855 0 :323
1st Qu.: 68.00 1st Qu.: 74.00 1st Qu.:0.3200 1st Qu.:2.671 1 : 86
Median : 82.00 Median : 88.00 Median :0.4150 Median :2.934 NA's: 1
Mean : 81.38 Mean : 92.11 Mean :0.4539 Mean :3.008
3rd Qu.: 95.00 3rd Qu.:108.00 3rd Qu.:0.5600 3rd Qu.:3.343
Max. :142.00 Max. :194.00 Max. :1.2300 Max. :4.421
NA's :8 NA's :12 NA's :235
------------------------------------------------------------
IPDNa$centre: 2
centre gender bmi age sbp
Min. :2 0:319 Min. :14.98 Min. : 36.00 Min. : 67.0
1st Qu.:2 1:248 1st Qu.:24.26 1st Qu.: 58.00 1st Qu.:125.8
Median :2 Median :28.08 Median : 68.00 Median :147.0
Mean :2 Mean :29.06 Mean : 70.48 Mean :146.8
3rd Qu.:2 3rd Qu.:33.22 3rd Qu.: 81.00 3rd Qu.:167.0
Max. :2 Max. :53.54 Max. :148.00 Max. :242.0
NA's :105 NA's :11
dbp hr lvef bnp afib
Min. : 29.00 Min. : 35.00 Min. :0.0600 Min. :1.845 0:433
1st Qu.: 66.00 1st Qu.: 68.00 1st Qu.:0.2100 1st Qu.:2.612 1:134
Median : 79.00 Median : 80.00 Median :0.3000 Median :2.908
Mean : 78.68 Mean : 82.29 Mean :0.3489 Mean :2.948
3rd Qu.: 92.00 3rd Qu.: 94.00 3rd Qu.:0.4300 3rd Qu.:3.248
Max. :136.00 Max. :229.00 Max. :1.6900 Max. :5.053
NA's :17 NA's :6 NA's :57
------------------------------------------------------------
IPDNa$centre: 3
centre gender bmi age sbp
Min. :3 0:150 Min. :16.42 Min. : 43.00 Min. : 70.0
1st Qu.:3 1: 60 1st Qu.:24.94 1st Qu.: 61.25 1st Qu.:109.0
Median :3 Median :27.76 Median : 69.00 Median :130.0
Mean :3 Mean :28.27 Mean : 71.95 Mean :129.2
3rd Qu.:3 3rd Qu.:31.58 3rd Qu.: 80.75 3rd Qu.:147.5
Max. :3 Max. :42.85 Max. :134.00 Max. :221.0
NA's :90 NA's :3
dbp hr lvef bnp afib
Min. : 42.00 Min. : 44.00 Min. :0.0800 Min. :2.036 0 : 0
1st Qu.: 68.00 1st Qu.: 71.00 1st Qu.:0.2400 1st Qu.:2.860 1 : 0
Median : 76.00 Median : 83.00 Median :0.3300 Median :3.276 NA's:210
Mean : 75.41 Mean : 85.55 Mean :0.3670 Mean :3.325
3rd Qu.: 84.00 3rd Qu.: 99.00 3rd Qu.:0.4375 3rd Qu.:3.713
Max. :103.00 Max. :160.00 Max. :1.1600 Max. :5.258
NA's :4 NA's :3
------------------------------------------------------------
IPDNa$centre: 4
centre gender bmi age sbp
Min. :4 0:232 Min. :14.39 Min. : 41.00 Min. : 57.0
1st Qu.:4 1:143 1st Qu.:23.18 1st Qu.: 66.00 1st Qu.:122.2
Median :4 Median :25.78 Median : 74.00 Median :141.0
Mean :4 Mean :26.72 Mean : 73.83 Mean :141.7
3rd Qu.:4 3rd Qu.:29.69 3rd Qu.: 81.00 3rd Qu.:159.0
Max. :4 Max. :52.27 Max. :106.00 Max. :264.0
NA's :9 NA's :5
dbp hr lvef bnp afib
Min. : 29.00 Min. : 40.00 Min. :0.1000 Min. :1.658 0 :135
1st Qu.: 76.00 1st Qu.: 76.00 1st Qu.:0.2900 1st Qu.:2.636 1 : 84
Median : 88.50 Median : 90.00 Median :0.3900 Median :2.905 NA's:156
Mean : 87.65 Mean : 94.49 Mean :0.4193 Mean :2.938
3rd Qu.:100.00 3rd Qu.:109.00 3rd Qu.:0.5000 3rd Qu.:3.241
Max. :163.00 Max. :202.00 Max. :1.3600 Max. :4.771
NA's :5 NA's :9 NA's :15
------------------------------------------------------------
IPDNa$centre: 5
centre gender bmi age sbp
Min. :5 0:59 Min. :17.74 Min. : 41.00 Min. : 86.0
1st Qu.:5 1:48 1st Qu.:26.01 1st Qu.: 62.00 1st Qu.:134.5
Median :5 Median :27.85 Median : 70.00 Median :153.0
Mean :5 Mean :28.71 Mean : 74.23 Mean :153.3
3rd Qu.:5 3rd Qu.:31.70 3rd Qu.: 82.00 3rd Qu.:162.5
Max. :5 Max. :39.11 Max. :176.00 Max. :246.0
NA's :1
dbp hr lvef bnp afib
Min. : 45.00 Min. : 45.0 Min. :0.2100 Min. : NA 0:48
1st Qu.: 74.00 1st Qu.: 83.0 1st Qu.:0.3600 1st Qu.: NA 1:59
Median : 87.00 Median :101.0 Median :0.4700 Median : NA
Mean : 86.73 Mean :105.0 Mean :0.4848 Mean :NaN
3rd Qu.: 99.50 3rd Qu.:124.5 3rd Qu.:0.5800 3rd Qu.: NA
Max. :131.00 Max. :198.0 Max. :1.2000 Max. : NA
NA's :107
------------------------------------------------------------
IPDNa$centre: 6
centre gender bmi age sbp dbp
Min. :6 0:150 Min. : NA Min. : 44.00 Min. : NA Min. : NA
1st Qu.:6 1:117 1st Qu.: NA 1st Qu.: 66.00 1st Qu.: NA 1st Qu.: NA
Median :6 Median : NA Median : 72.00 Median : NA Median : NA
Mean :6 Mean :NaN Mean : 74.09 Mean :NaN Mean :NaN
3rd Qu.:6 3rd Qu.: NA 3rd Qu.: 82.00 3rd Qu.: NA 3rd Qu.: NA
Max. :6 Max. : NA Max. :125.00 Max. : NA Max. : NA
NA's :267 NA's :267 NA's :267
hr lvef bnp afib
Min. : 35.00 Min. :0.1400 Min. : NA 0:160
1st Qu.: 74.00 1st Qu.:0.2900 1st Qu.: NA 1:107
Median : 93.00 Median :0.3700 Median : NA
Mean : 97.37 Mean :0.4131 Mean :NaN
3rd Qu.:116.00 3rd Qu.:0.5100 3rd Qu.: NA
Max. :284.00 Max. :0.9300 Max. : NA
NA's :1 NA's :267
------------------------------------------------------------
IPDNa$centre: 7
centre gender bmi age sbp
Min. :7 0: 97 Min. :16.66 Min. : 36.0 Min. : 55.0
1st Qu.:7 1:106 1st Qu.:23.11 1st Qu.: 60.0 1st Qu.:120.8
Median :7 Median :27.01 Median : 70.0 Median :138.0
Mean :7 Mean :27.33 Mean : 71.4 Mean :140.6
3rd Qu.:7 3rd Qu.:30.79 3rd Qu.: 81.0 3rd Qu.:159.2
Max. :7 Max. :42.73 Max. :125.0 Max. :238.0
NA's :1 NA's :3
dbp hr lvef bnp afib
Min. : 25.00 Min. : 40.00 Min. :0.1500 Min. :1.165 0:127
1st Qu.: 64.00 1st Qu.: 66.00 1st Qu.:0.3350 1st Qu.:1.972 1: 76
Median : 78.00 Median : 80.00 Median :0.4400 Median :2.387
Mean : 76.78 Mean : 85.27 Mean :0.4937 Mean :2.463
3rd Qu.: 88.50 3rd Qu.: 98.25 3rd Qu.:0.6000 3rd Qu.:2.825
Max. :129.00 Max. :207.00 Max. :1.4000 Max. :6.454
NA's :4 NA's :3 NA's :1
------------------------------------------------------------
IPDNa$centre: 8
centre gender bmi age sbp
Min. :8 0:235 Min. :17.05 Min. : 37.0 Min. : 50
1st Qu.:8 1:119 1st Qu.:23.41 1st Qu.: 58.0 1st Qu.:106
Median :8 Median :27.21 Median : 67.0 Median :125
Mean :8 Mean :27.43 Mean : 70.1 Mean :129
3rd Qu.:8 3rd Qu.:30.76 3rd Qu.: 80.0 3rd Qu.:151
Max. :8 Max. :47.71 Max. :153.0 Max. :233
NA's :157 NA's :5 NA's :57
dbp hr lvef bnp afib
Min. : 6.00 Min. : 39.00 Min. :0.0900 Min. :2.168 0 :149
1st Qu.: 62.75 1st Qu.: 69.00 1st Qu.:0.2500 1st Qu.:2.756 1 :127
Median : 75.00 Median : 85.00 Median :0.3400 Median :3.080 NA's: 78
Mean : 76.04 Mean : 86.81 Mean :0.3775 Mean :3.099
3rd Qu.: 89.00 3rd Qu.:100.00 3rd Qu.:0.4675 3rd Qu.:3.407
Max. :129.00 Max. :180.00 Max. :1.2500 Max. :4.391
NA's :58 NA's :67 NA's :44
------------------------------------------------------------
IPDNa$centre: 9
centre gender bmi age sbp
Min. :9 0:126 Min. :16.79 Min. : 43.0 Min. : 42.0
1st Qu.:9 1: 11 1st Qu.:23.17 1st Qu.: 61.0 1st Qu.:108.0
Median :9 Median :25.57 Median : 72.0 Median :131.0
Mean :9 Mean :26.14 Mean : 73.3 Mean :134.9
3rd Qu.:9 3rd Qu.:28.80 3rd Qu.: 83.0 3rd Qu.:155.0
Max. :9 Max. :38.70 Max. :115.0 Max. :305.0
NA's :1
dbp hr lvef bnp afib
Min. : 19.00 Min. : 47.00 Min. :0.1500 Min. :1.958 0:69
1st Qu.: 64.00 1st Qu.: 82.00 1st Qu.:0.3100 1st Qu.:2.630 1:68
Median : 79.00 Median : 94.00 Median :0.3700 Median :2.888
Mean : 77.86 Mean : 99.04 Mean :0.3797 Mean :2.927
3rd Qu.: 91.00 3rd Qu.:116.00 3rd Qu.:0.4500 3rd Qu.:3.187
Max. :125.00 Max. :188.00 Max. :0.8000 Max. :4.099
------------------------------------------------------------
IPDNa$centre: 10
centre gender bmi age sbp
Min. :10 0:25 Min. : NA Min. : 29.00 Min. : 50.0
1st Qu.:10 1:23 1st Qu.: NA 1st Qu.: 39.00 1st Qu.:112.8
Median :10 Median : NA Median : 54.00 Median :142.5
Mean :10 Mean :NaN Mean : 61.42 Mean :147.5
3rd Qu.:10 3rd Qu.: NA 3rd Qu.: 71.50 3rd Qu.:181.2
Max. :10 Max. : NA Max. :154.00 Max. :269.0
NA's :48
dbp hr lvef bnp afib
Min. : 39.00 Min. : 60.0 Min. :0.2100 Min. : NA 0:36
1st Qu.: 72.00 1st Qu.: 89.5 1st Qu.:0.3150 1st Qu.: NA 1:12
Median : 85.00 Median : 99.0 Median :0.5050 Median : NA
Mean : 84.69 Mean :105.0 Mean :0.5773 Mean :NaN
3rd Qu.:100.00 3rd Qu.:117.8 3rd Qu.:0.6575 3rd Qu.: NA
Max. :131.00 Max. :175.0 Max. :2.2600 Max. : NA
NA's :2 NA's :48
------------------------------------------------------------
IPDNa$centre: 11
centre gender bmi age sbp
Min. :11 0:140 Min. :16.79 Min. : 39.00 Min. : 54.0
1st Qu.:11 1: 68 1st Qu.:24.16 1st Qu.: 55.00 1st Qu.:101.0
Median :11 Median :27.66 Median : 65.00 Median :118.5
Mean :11 Mean :27.25 Mean : 67.02 Mean :123.3
3rd Qu.:11 3rd Qu.:30.16 3rd Qu.: 76.00 3rd Qu.:142.2
Max. :11 Max. :38.00 Max. :162.00 Max. :224.0
NA's :49
dbp hr lvef bnp afib
Min. : 32.0 Min. : 32.0 Min. :0.0900 Min. : NA 0:160
1st Qu.: 61.0 1st Qu.: 71.0 1st Qu.:0.2500 1st Qu.: NA 1: 48
Median : 74.0 Median : 86.0 Median :0.3500 Median : NA
Mean : 74.4 Mean : 87.2 Mean :0.3715 Mean :NaN
3rd Qu.: 88.0 3rd Qu.: 99.0 3rd Qu.:0.4400 3rd Qu.: NA
Max. :114.0 Max. :159.0 Max. :1.4400 Max. : NA
NA's :1 NA's :208
------------------------------------------------------------
IPDNa$centre: 12
centre gender bmi age sbp
Min. :12 0:424 Min. :15.52 Min. : 41.00 Min. : 47.0
1st Qu.:12 1:198 1st Qu.:23.95 1st Qu.: 61.00 1st Qu.:107.0
Median :12 Median :27.12 Median : 69.00 Median :126.0
Mean :12 Mean :27.50 Mean : 71.05 Mean :127.1
3rd Qu.:12 3rd Qu.:30.49 3rd Qu.: 79.00 3rd Qu.:147.0
Max. :12 Max. :47.07 Max. :141.00 Max. :261.0
NA's :167 NA's :3
dbp hr lvef bnp afib
Min. : 21.00 Min. : 40.00 Min. :0.1300 Min. : NA 0:346
1st Qu.: 65.00 1st Qu.: 73.00 1st Qu.:0.2600 1st Qu.: NA 1:276
Median : 76.00 Median : 85.00 Median :0.3500 Median : NA
Mean : 75.08 Mean : 88.98 Mean :0.3741 Mean :NaN
3rd Qu.: 86.00 3rd Qu.:100.00 3rd Qu.:0.4500 3rd Qu.: NA
Max. :130.00 Max. :166.00 Max. :1.1300 Max. : NA
NA's :3 NA's :9 NA's :622
------------------------------------------------------------
IPDNa$centre: 13
centre gender bmi age sbp
Min. :13 0:36 Min. :17.37 Min. :26.00 Min. : 76.0
1st Qu.:13 1:42 1st Qu.:22.69 1st Qu.:45.00 1st Qu.:103.0
Median :13 Median :25.90 Median :50.50 Median :113.0
Mean :13 Mean :27.79 Mean :52.58 Mean :115.5
3rd Qu.:13 3rd Qu.:32.14 3rd Qu.:57.50 3rd Qu.:126.2
Max. :13 Max. :48.77 Max. :96.00 Max. :161.0
NA's :47
dbp hr lvef bnp afib
Min. : 42.00 Min. : 50.00 Min. :0.1100 Min. : NA 0 : 0
1st Qu.: 63.00 1st Qu.: 70.50 1st Qu.:0.2025 1st Qu.: NA 1 : 0
Median : 70.50 Median : 82.50 Median :0.2550 Median : NA NA's:78
Mean : 73.09 Mean : 84.69 Mean :0.2728 Mean :NaN
3rd Qu.: 82.00 3rd Qu.: 97.75 3rd Qu.:0.3300 3rd Qu.: NA
Max. :108.00 Max. :156.00 Max. :0.6000 Max. : NA
NA's :78
------------------------------------------------------------
IPDNa$centre: 14
centre gender bmi age sbp
Min. :14 0:333 Min. :16.49 Min. : 53.0 Min. : 59.0
1st Qu.:14 1:337 1st Qu.:23.66 1st Qu.: 71.0 1st Qu.:122.0
Median :14 Median :27.04 Median : 77.0 Median :141.0
Mean :14 Mean :27.43 Mean : 78.1 Mean :142.1
3rd Qu.:14 3rd Qu.:30.28 3rd Qu.: 85.0 3rd Qu.:160.0
Max. :14 Max. :45.61 Max. :111.0 Max. :240.0
NA's :514 NA's :1 NA's :6
dbp hr lvef bnp afib
Min. : 19.00 Min. : 40.00 Min. :0.1500 Min. : NA 0 :302
1st Qu.: 68.00 1st Qu.: 70.00 1st Qu.:0.3500 1st Qu.: NA 1 :367
Median : 80.00 Median : 83.00 Median :0.4600 Median : NA NA's: 1
Mean : 79.28 Mean : 86.27 Mean :0.4789 Mean :NaN
3rd Qu.: 91.00 3rd Qu.: 99.75 3rd Qu.:0.5800 3rd Qu.: NA
Max. :126.00 Max. :174.00 Max. :1.2200 Max. : NA
NA's :6 NA's :12 NA's :670
------------------------------------------------------------
IPDNa$centre: 15
centre gender bmi age sbp
Min. :15 0:490 Min. :13.88 Min. : 29.00 Min. : 57.0
1st Qu.:15 1:510 1st Qu.:20.43 1st Qu.: 57.00 1st Qu.:111.0
Median :15 Median :22.62 Median : 67.00 Median :130.0
Mean :15 Mean :22.96 Mean : 68.92 Mean :131.4
3rd Qu.:15 3rd Qu.:25.20 3rd Qu.: 78.00 3rd Qu.:151.2
Max. :15 Max. :36.33 Max. :152.00 Max. :230.0
NA's :130 NA's :16
dbp hr lvef bnp afib
Min. : 18.00 Min. : 37.00 Min. :0.1000 Min. :1.524 0 :803
1st Qu.: 65.00 1st Qu.: 73.00 1st Qu.:0.2600 1st Qu.:2.325 1 :194
Median : 79.00 Median : 89.00 Median :0.3500 Median :2.803 NA's: 3
Mean : 78.53 Mean : 94.07 Mean :0.3759 Mean :2.904
3rd Qu.: 91.00 3rd Qu.:111.00 3rd Qu.:0.4500 3rd Qu.:3.405
Max. :146.00 Max. :249.00 Max. :1.6900 Max. :5.299
NA's :17 NA's :20 NA's :817
------------------------------------------------------------
IPDNa$centre: 16
centre gender bmi age sbp
Min. :16 0:798 Min. :12.48 Min. : 18.00 Min. : 56.0
1st Qu.:16 1:295 1st Qu.:21.02 1st Qu.: 42.00 1st Qu.:103.0
Median :16 Median :23.41 Median : 53.00 Median :117.0
Mean :16 Mean :23.87 Mean : 56.91 Mean :117.5
3rd Qu.:16 3rd Qu.:26.28 3rd Qu.: 67.00 3rd Qu.:131.0
Max. :16 Max. :41.99 Max. :147.00 Max. :185.0
dbp hr lvef bnp afib
Min. : 33.00 Min. : 40.00 Min. :0.1100 Min. : NA 0:932
1st Qu.: 61.00 1st Qu.: 68.00 1st Qu.:0.3000 1st Qu.: NA 1:161
Median : 70.00 Median : 78.00 Median :0.3900 Median : NA
Mean : 70.23 Mean : 80.13 Mean :0.4146 Mean :NaN
3rd Qu.: 79.00 3rd Qu.: 91.00 3rd Qu.:0.5000 3rd Qu.: NA
Max. :110.00 Max. :156.00 Max. :1.2900 Max. : NA
NA's :1093
------------------------------------------------------------
IPDNa$centre: 17
centre gender bmi age sbp
Min. :17 0:9 Min. : 10.86 Min. : 56.00 Min. : 86.0
1st Qu.:17 1:9 1st Qu.: 26.96 1st Qu.: 59.75 1st Qu.:151.2
Median :17 Median : 38.58 Median : 69.00 Median :170.5
Mean :17 Mean : 45.08 Mean : 71.11 Mean :166.8
3rd Qu.:17 3rd Qu.: 53.67 3rd Qu.: 74.50 3rd Qu.:195.5
Max. :17 Max. :116.24 Max. :108.00 Max. :227.0
NA's :1
dbp hr lvef bnp afib
Min. : 47.00 Min. : 27.00 Min. :0.1300 Min. : 0.9971 0:9
1st Qu.: 70.50 1st Qu.: 75.75 1st Qu.:0.3425 1st Qu.: 1.8052 1:9
Median : 88.50 Median : 91.50 Median :0.5100 Median : 2.6966
Mean : 88.33 Mean : 96.67 Mean :0.6950 Mean : 3.2260
3rd Qu.:107.75 3rd Qu.:104.00 3rd Qu.:0.8150 3rd Qu.: 3.4763
Max. :120.00 Max. :216.00 Max. :1.8800 Max. :10.1229
NA's :4
------------------------------------------------------------
IPDNa$centre: 18
centre gender bmi age sbp
Min. :18 0:1103 Min. :15.56 Min. : 35.00 Min. : 22.0
1st Qu.:18 1: 731 1st Qu.:24.91 1st Qu.: 61.00 1st Qu.:110.0
Median :18 Median :28.10 Median : 70.00 Median :135.0
Mean :18 Mean :28.52 Mean : 71.07 Mean :136.3
3rd Qu.:18 3rd Qu.:31.74 3rd Qu.: 80.00 3rd Qu.:160.0
Max. :18 Max. :49.80 Max. :130.00 Max. :278.0
NA's :357 NA's :11
dbp hr lvef bnp afib
Min. : 14.00 Min. : 29 Min. :0.1100 Min. :1.688 0 :1392
1st Qu.: 66.00 1st Qu.: 72 1st Qu.:0.2800 1st Qu.:2.420 1 : 435
Median : 79.00 Median : 88 Median :0.3700 Median :2.812 NA's: 7
Mean : 79.38 Mean : 93 Mean :0.4032 Mean :2.790
3rd Qu.: 93.00 3rd Qu.:109 3rd Qu.:0.4900 3rd Qu.:3.109
Max. :152.00 Max. :251 Max. :1.5200 Max. :4.365
NA's :11 NA's :6 NA's :1695
------------------------------------------------------------
IPDNa$centre: 19
centre gender bmi age sbp
Min. :19 0:162 Min. :15.40 Min. : 42.00 Min. : 61.0
1st Qu.:19 1:196 1st Qu.:24.49 1st Qu.: 65.00 1st Qu.:118.0
Median :19 Median :27.38 Median : 72.00 Median :140.0
Mean :19 Mean :28.10 Mean : 73.33 Mean :141.4
3rd Qu.:19 3rd Qu.:31.52 3rd Qu.: 80.00 3rd Qu.:163.0
Max. :19 Max. :50.25 Max. :119.00 Max. :244.0
NA's :26
dbp hr lvef bnp afib
Min. : 37.00 Min. : 29.00 Min. :0.1100 Min. :1.550 0:248
1st Qu.: 71.00 1st Qu.: 74.00 1st Qu.:0.2700 1st Qu.:2.180 1:110
Median : 82.00 Median : 91.50 Median :0.3600 Median :2.500
Mean : 81.68 Mean : 97.14 Mean :0.3812 Mean :2.376
3rd Qu.: 93.00 3rd Qu.:116.00 3rd Qu.:0.4600 3rd Qu.:2.696
Max. :133.00 Max. :250.00 Max. :0.9800 Max. :2.954
NA's :354
------------------------------------------------------------
IPDNa$centre: 20
centre gender bmi age sbp
Min. :20 0:25 Min. :21.66 Min. : 54.00 Min. : 72.0
1st Qu.:20 1:29 1st Qu.:26.31 1st Qu.: 69.00 1st Qu.:125.0
Median :20 Median :29.90 Median : 76.00 Median :157.0
Mean :20 Mean :29.46 Mean : 76.57 Mean :151.8
3rd Qu.:20 3rd Qu.:32.37 3rd Qu.: 83.50 3rd Qu.:179.0
Max. :20 Max. :42.69 Max. :101.00 Max. :223.0
NA's :3 NA's :1
dbp hr lvef bnp afib
Min. : 55.00 Min. : 56.00 Min. :0.1200 Min. : NA 0 :23
1st Qu.: 74.00 1st Qu.: 81.00 1st Qu.:0.2125 1st Qu.: NA 1 :30
Median : 89.00 Median : 91.00 Median :0.3400 Median : NA NA's: 1
Mean : 85.43 Mean : 91.91 Mean :0.3746 Mean :NaN
3rd Qu.: 95.00 3rd Qu.:102.00 3rd Qu.:0.4775 3rd Qu.: NA
Max. :120.00 Max. :148.00 Max. :1.2400 Max. : NA
NA's :1 NA's :1 NA's :54
------------------------------------------------------------
IPDNa$centre: 21
centre gender bmi age sbp
Min. :21 0:380 Min. :15.52 Min. : 33.00 Min. : 39.0
1st Qu.:21 1:208 1st Qu.:23.80 1st Qu.: 62.75 1st Qu.:107.0
Median :21 Median :27.01 Median : 71.00 Median :128.0
Mean :21 Mean :27.86 Mean : 72.63 Mean :131.8
3rd Qu.:21 3rd Qu.:31.03 3rd Qu.: 80.00 3rd Qu.:155.0
Max. :21 Max. :47.76 Max. :148.00 Max. :246.0
NA's :59 NA's :2
dbp hr lvef bnp afib
Min. : 17.00 Min. : 39.00 Min. :0.0400 Min. :1.943 0 :423
1st Qu.: 65.00 1st Qu.: 73.00 1st Qu.:0.2000 1st Qu.:2.236 1 :164
Median : 78.00 Median : 87.00 Median :0.2900 Median :2.520 NA's: 1
Mean : 77.45 Mean : 89.99 Mean :0.3371 Mean :2.545
3rd Qu.: 89.00 3rd Qu.:103.00 3rd Qu.:0.4100 3rd Qu.:2.794
Max. :122.00 Max. :228.00 Max. :1.5000 Max. :3.429
NA's :2 NA's :571
------------------------------------------------------------
IPDNa$centre: 22
centre gender bmi age sbp
Min. :22 0:307 Min. :14.94 Min. : 44.00 Min. : 65.0
1st Qu.:22 1:344 1st Qu.:24.79 1st Qu.: 67.00 1st Qu.:121.0
Median :22 Median :28.00 Median : 74.00 Median :139.0
Mean :22 Mean :28.70 Mean : 75.55 Mean :141.1
3rd Qu.:22 3rd Qu.:32.22 3rd Qu.: 83.00 3rd Qu.:161.0
Max. :22 Max. :45.96 Max. :123.00 Max. :250.0
NA's :156 NA's :14
dbp hr lvef bnp afib
Min. : 36.00 Min. : 31.00 Min. :0.1300 Min. :1.611 0 :406
1st Qu.: 72.00 1st Qu.: 79.50 1st Qu.:0.3000 1st Qu.:2.495 1 :234
Median : 82.00 Median : 94.00 Median :0.3900 Median :2.825 NA's: 11
Mean : 82.11 Mean : 97.27 Mean :0.4178 Mean :2.905
3rd Qu.: 92.00 3rd Qu.:112.00 3rd Qu.:0.5000 3rd Qu.:3.290
Max. :139.00 Max. :227.00 Max. :1.1600 Max. :4.899
NA's :15 NA's :12 NA's :476
------------------------------------------------------------
IPDNa$centre: 23
centre gender bmi age sbp
Min. :23 0:251 Min. :19.35 Min. : 46.00 Min. : 57.0
1st Qu.:23 1:204 1st Qu.:26.83 1st Qu.: 66.00 1st Qu.:125.0
Median :23 Median :30.06 Median : 74.00 Median :145.0
Mean :23 Mean :30.77 Mean : 74.76 Mean :146.3
3rd Qu.:23 3rd Qu.:33.81 3rd Qu.: 82.00 3rd Qu.:166.0
Max. :23 Max. :53.67 Max. :109.00 Max. :242.0
NA's :7
dbp hr lvef bnp afib
Min. : 25.00 Min. : 41.00 Min. :0.0900 Min. :2.693 0 :240
1st Qu.: 74.00 1st Qu.: 76.00 1st Qu.:0.2600 1st Qu.:3.460 1 :214
Median : 85.00 Median : 90.00 Median :0.3300 Median :3.753 NA's: 1
Mean : 84.86 Mean : 95.97 Mean :0.3553 Mean :3.819
3rd Qu.: 96.00 3rd Qu.:110.00 3rd Qu.:0.4200 3rd Qu.:4.271
Max. :137.00 Max. :202.00 Max. :0.8900 Max. :5.389
NA's :1 NA's :393
------------------------------------------------------------
IPDNa$centre: 24
centre gender bmi age sbp
Min. :24 0:206 Min. :16.31 Min. : 38.00 Min. : 43.0
1st Qu.:24 1: 88 1st Qu.:23.99 1st Qu.: 56.00 1st Qu.:110.0
Median :24 Median :26.99 Median : 66.00 Median :136.0
Mean :24 Mean :27.53 Mean : 67.32 Mean :135.5
3rd Qu.:24 3rd Qu.:30.58 3rd Qu.: 77.00 3rd Qu.:159.0
Max. :24 Max. :44.42 Max. :128.00 Max. :257.0
NA's :13 NA's :1
dbp hr lvef bnp afib
Min. : 16.00 Min. : 37.00 Min. :0.1100 Min. :1.949 0:234
1st Qu.: 61.00 1st Qu.: 73.00 1st Qu.:0.2300 1st Qu.:2.470 1: 60
Median : 76.00 Median : 88.00 Median :0.3000 Median :2.911
Mean : 74.45 Mean : 93.09 Mean :0.3323 Mean :2.941
3rd Qu.: 90.00 3rd Qu.:110.00 3rd Qu.:0.4000 3rd Qu.:3.381
Max. :117.00 Max. :192.00 Max. :1.0400 Max. :4.187
NA's :1 NA's :1 NA's :237
------------------------------------------------------------
IPDNa$centre: 25
centre gender bmi age sbp
Min. :25 0:286 Min. :17.16 Min. : 38.00 Min. : 51.0
1st Qu.:25 1:111 1st Qu.:25.84 1st Qu.: 58.00 1st Qu.:112.0
Median :25 Median :28.94 Median : 66.00 Median :130.0
Mean :25 Mean :28.92 Mean : 68.37 Mean :132.9
3rd Qu.:25 3rd Qu.:31.84 3rd Qu.: 77.00 3rd Qu.:155.0
Max. :25 Max. :45.52 Max. :126.00 Max. :223.0
NA's :5 NA's :2
dbp hr lvef bnp afib
Min. : 26.00 Min. : 44.00 Min. :0.1000 Min. : NA 0 :325
1st Qu.: 66.00 1st Qu.: 74.00 1st Qu.:0.2700 1st Qu.: NA 1 : 70
Median : 80.00 Median : 87.00 Median :0.3400 Median : NA NA's: 2
Mean : 78.62 Mean : 90.36 Mean :0.3727 Mean :NaN
3rd Qu.: 92.00 3rd Qu.:105.00 3rd Qu.:0.4500 3rd Qu.: NA
Max. :138.00 Max. :185.00 Max. :1.1400 Max. : NA
NA's :2 NA's :2 NA's :397
------------------------------------------------------------
IPDNa$centre: 26
centre gender bmi age sbp
Min. :26 0:182 Min. :17.16 Min. : 35.0 Min. : 62.0
1st Qu.:26 1:113 1st Qu.:24.31 1st Qu.: 59.0 1st Qu.:110.0
Median :26 Median :27.35 Median : 69.0 Median :131.0
Mean :26 Mean :27.99 Mean : 70.9 Mean :132.1
3rd Qu.:26 3rd Qu.:31.04 3rd Qu.: 80.0 3rd Qu.:151.5
Max. :26 Max. :46.67 Max. :140.0 Max. :215.0
NA's :33
dbp hr lvef bnp afib
Min. : 32.00 Min. : 32.0 Min. :0.1400 Min. :2.060 0:214
1st Qu.: 66.00 1st Qu.: 66.5 1st Qu.:0.2900 1st Qu.:2.679 1: 81
Median : 77.00 Median : 82.0 Median :0.4000 Median :3.029
Mean : 77.74 Mean : 88.7 Mean :0.4344 Mean :3.027
3rd Qu.: 90.00 3rd Qu.:108.5 3rd Qu.:0.5300 3rd Qu.:3.274
Max. :125.00 Max. :215.0 Max. :1.1600 Max. :4.543
NA's :194
------------------------------------------------------------
IPDNa$centre: 27
centre gender bmi age sbp
Min. :27 0:143 Min. :18.16 Min. : 43.00 Min. : 54.0
1st Qu.:27 1:160 1st Qu.:25.60 1st Qu.: 65.50 1st Qu.:122.0
Median :27 Median :28.26 Median : 74.00 Median :142.0
Mean :27 Mean :28.98 Mean : 74.56 Mean :145.9
3rd Qu.:27 3rd Qu.:31.53 3rd Qu.: 84.00 3rd Qu.:170.0
Max. :27 Max. :53.58 Max. :117.00 Max. :272.0
NA's :32 NA's :1
dbp hr lvef bnp afib
Min. : 36.00 Min. : 31.00 Min. :0.150 Min. :1.791 0:218
1st Qu.: 71.00 1st Qu.: 67.00 1st Qu.:0.280 1st Qu.:2.523 1: 85
Median : 84.00 Median : 84.00 Median :0.380 Median :3.128
Mean : 84.69 Mean : 88.18 Mean :0.405 Mean :3.071
3rd Qu.: 97.00 3rd Qu.:105.00 3rd Qu.:0.500 3rd Qu.:3.447
Max. :150.00 Max. :207.00 Max. :0.940 Max. :5.280
NA's :1 NA's :238
------------------------------------------------------------
IPDNa$centre: 28
centre gender bmi age sbp
Min. :28 0:45 Min. :19.67 Min. : 47.00 Min. : 85.0
1st Qu.:28 1:44 1st Qu.:24.63 1st Qu.: 66.00 1st Qu.:121.0
Median :28 Median :28.07 Median : 75.00 Median :132.0
Mean :28 Mean :28.87 Mean : 75.73 Mean :136.5
3rd Qu.:28 3rd Qu.:33.07 3rd Qu.: 83.00 3rd Qu.:149.0
Max. :28 Max. :41.96 Max. :129.00 Max. :222.0
dbp hr lvef bnp afib
Min. : 56.00 Min. : 41.00 Min. :0.1500 Min. :1.385 0:45
1st Qu.: 72.00 1st Qu.: 73.00 1st Qu.:0.2700 1st Qu.:2.196 1:44
Median : 85.00 Median : 87.00 Median :0.3800 Median :2.423
Mean : 84.55 Mean : 90.34 Mean :0.4274 Mean :2.528
3rd Qu.: 95.00 3rd Qu.:107.00 3rd Qu.:0.5000 3rd Qu.:2.818
Max. :130.00 Max. :174.00 Max. :1.7300 Max. :3.893
NA's :34
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