Outcomes of pregnancies exposed to coumarin derivatives. The aim is to investigate whether exposition to coumarin derivatives increases the probability of spontaneous abortions. Apart from spontaneous abortion, pregnancy may end in induced abortion or live birth. Moreover, data are left-truncated as women usually enter the study several weeks after conception.
A data frame with 1186 observations on the following 5 variables.
Entry times into the cohort
Group. 0: control, 1: exposed to coumarin derivatives
Cause of failure. 1: induced abortion, 2: life birth, 3: spontaneous abortion
Meiester, R. and Schaefer, C (2008). Statistical methods for estimating the probability of spontaneous abortion in observational studies – Analyzing pregnancies exposed to coumarin derivatives. Reproductive Toxicology, 26, 31–35
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