as.nonmem2rx | R Documentation |
Convert a model to a nonmem2rx model
as.nonmem2rx(model1, model2, compress = TRUE)
model1 |
Input model 1 |
model2 |
Input model 2 |
compress |
boolean to compress the ui at the end |
nonmem2rx model
Matthew L. Fidler
mod <- nonmem2rx(system.file("mods/cpt/runODE032.ctl", package="nonmem2rx"),
determineError=FALSE, lst=".res", save=FALSE)
mod2 <-function() {
ini({
lcl <- 1.37034036528946
lvc <- 4.19814911033061
lq <- 1.38003493562413
lvp <- 3.87657341967489
RSV <- c(0, 0.196446108190896, 1)
eta.cl ~ 0.101251418415006
eta.v ~ 0.0993872449483344
eta.q ~ 0.101302674763154
eta.v2 ~ 0.0730497519364148
})
model({
cmt(CENTRAL)
cmt(PERI)
cl <- exp(lcl + eta.cl)
v <- exp(lvc + eta.v)
q <- exp(lq + eta.q)
v2 <- exp(lvp + eta.v2)
v1 <- v
scale1 <- v
k21 <- q/v2
k12 <- q/v
d/dt(CENTRAL) <- k21 * PERI - k12 * CENTRAL - cl * CENTRAL/v1
d/dt(PERI) <- -k21 * PERI + k12 * CENTRAL
f <- CENTRAL/scale1
f ~ prop(RSV)
})
}
new <- try(as.nonmem2rx(mod2, mod))
if (!inherits(new, "try-error")) print(new, page=1)
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