endosim: Simulated endocrine data.

endosimR Documentation

Simulated endocrine data.


The endosim data set was simulated based on the data analyzed in Rodriguez-Alvarez et al. (2011a,b) and presented in Botana et al. (2007) and Tome et al. (2008). The aim of these studies was to use the Body Mass Index (BMI) to detect patients having a higher risk of cardiovascular problems, ascertaining the possible effect of age and gender on the accuracy of this measure.




A data frame with 2840 observations on the following 4 variables.


patient's gender. Factor with Male and Female levels.


patient's age.


true disease status (presence/absence of two of more cardiovascular risk factors according to the International Diabetes Federation). Numerical vector (0=absence, 1=presence).


patient's body mass index.


Botana, M.A., Mato, J.A., Cadarso-Suarez, C., Tome, M.A., Perez-Fernandez, R., Fernandez-Mario, A., Rego-Iraeta, A., Solache, I. (2007). Overweight, obesity and central obesity prevalences in the region of Galicia in Northwest Spain. Obesity and Metabolism, 3, 106–115.

Tome, M.A., Botana, M.A., Cadarso-Suarez, C., Rego-Iraeta, A., Fernandez-Mario, A., Mato, J.A, Solache, I., Perez-Fernandez, R. (2008). Prevalence of metabolic syndrome in Galicia (NW Spain) on four alternative definitions and association with insulin resistance. Journal of Endocrinological Investigation, 32, 505–511.


Rodriguez-Alvarez, M.X., Roca-Pardinas, J. and Cadarso-Suarez, C. (2011a). ROC curve and covariates: extending induced methodology to the non-parametric framework. Statistics and Computing, 21(4), 483–499.

Rodriguez- Alvarez, M.X., Roca-Pardinas, J. and Cadarso-Suarez, C. (2011b). A new flexible direct ROC regression model - Application to the detection of cardiovascular risk factors by anthropometric measures. Computational Statistics and Data Analysis, 55(12), 3257–3270.



npROCRegression documentation built on Aug. 31, 2023, 5:15 p.m.