pact: Predictive Analysis of Clinical Trials

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A prediction-based approach to the analysis of data from randomized clinical trials is implemented. Based on response and covariate data from a randomized clinical trial comparing a new experimental treatment E versus a control C, the objective is to develop and internally validate a model that can identify subjects likely to benefit from E rather than C. Currently, survival and binary response types are permitted.

Author
Jyothi Subramanian [aut, cre], Richard Simon [aut]
Date of publication
2016-04-15 23:39:12
Maintainer
Jyothi Subramanian <subramanianj01@gmail.com>
License
GPL-3
Version
0.5.0
URLs

View on CRAN

Man pages

EORTC10994
EORTC10994 dataset
eval.pact.cv
Evaluation functions for cross-validated predictions
GSE10846
GSE10846 dataset
KfoldCV
Split a dataset into k parts for k-fold cross-validation
overall.analysis
Overall statistics and inference
pact
Predictive Analysis of Clinical Trials
pact.cv
Cross-validation for pact
pact.fit
Fits a predictive model to the full dataset
predict.pact
Predictions from a predictive model fit
print.eval.cv
Print an object of class 'eval.cv'
print.pact
Print an object of class 'pact'
prostateCancer
Prostate cancer dataset
summary.pact
Summarize a predictive model fit

Files in this package

pact
pact/inst
pact/inst/doc
pact/inst/doc/pact_vignette.Rnw
pact/inst/doc/pact_vignette.R
pact/inst/doc/pact_vignette.pdf
pact/NAMESPACE
pact/data
pact/data/GSE10846.RData
pact/data/EORTC10994.RData
pact/data/prostateCancer.RData
pact/R
pact/R/pact.R
pact/vignettes
pact/vignettes/pact_vignette.Rnw
pact/MD5
pact/build
pact/build/vignette.rds
pact/DESCRIPTION
pact/man
pact/man/overall.analysis.Rd
pact/man/GSE10846.Rd
pact/man/pact.Rd
pact/man/EORTC10994.Rd
pact/man/KfoldCV.Rd
pact/man/print.eval.cv.Rd
pact/man/pact.cv.Rd
pact/man/summary.pact.Rd
pact/man/pact.fit.Rd
pact/man/eval.pact.cv.Rd
pact/man/print.pact.Rd
pact/man/prostateCancer.Rd
pact/man/predict.pact.Rd