binding2to1: Generate a 2:1 Binding Curve

In pbm: Protein Binding Models

Description

Returns a response value for given parameters at time, t.

Usage

binding2to1(
  t,
  t0,
  conc,
  kon1,
  koff1,
  rmax1,
  kon2,
  koff2,
  rmax2,
  drift = 0,
  offset = 0,
  doffset = 0
)

Arguments

t	Time.
t0	Time of dissociation.
conc	Analyte concentration.
kon1	Kon binding constant for first component.
koff1	Koff binding constant for first component.
rmax1	Maximum response, Rmax, for first component.
kon2	Kon binding constant for second component.
koff2	Koff binding constant for second component.
rmax2	Maximum response, Rmax, for second component.
drift	Optional. Parameter to add a linear baseline drift.
offset	Optional. Applies a global offset to the response value.
doffset	Optional. Applies an offset at the start of dissociation.

Examples

time <- seq(1,2000)
curve <- binding2to1(time,1000,900e-9,10000,0.01,0.4,2000,0.0003,0.5)
plot(curve)

Example output

pbm documentation built on March 28, 2021, 5:05 p.m.