quadfactor: Internal utility to calculate a constant quadratic factor for...

In pedgene: Gene-Level Variant Association Tests for Pedigree Data

Internal utility to calculate a constant quadratic factor for gene-level statistics variances, over all pedigrees

Description

Internal utility to calculate a constant quadratic factor for gene-level statistics variances over all pedigrees, for either autosomes or X chromosome

Usage

quadfactor(kinmat, chrom, resid, sex, male.dose)

Arguments

kinmat	A kinship matrix for one or more pedigrees
chrom	character string for chromosome number, if "X", the method accounts for sex code
resid	the residual based on the trait minus the group mean or adjusted trait value for each subject
sex	See pedgene
male.dose	See pedgene

Value

Constant quadratic factor for gene-level statistics variances, for autosomes and X chromosome

Author(s)

Daniel J. Schaid, Mayo Clinic ([e-mail]).

See Also

pedgene, kinship

pedgene documentation built on Oct. 18, 2022, 9:07 a.m.