simulated_families: Processed Family Data

In penetrance: Methods for Penetrance Estimation in Family-Based Studies

Processed Family Data

Description

A dataset containing processed information about the first simulated 130 families. These families are referenced in the vigniette simulation_study.Rmd and using_penetrance.Rmd The user must specify the pedigree argument as a data frame which contains the family data (see test_fam). The family data must be in the correct format with the following columns:

Usage

simulated_families

Format

A list of processed family data.

Details

ID

A numeric value representing the unique identifier for each individual. There should be no duplicated entries.

Sex

A numeric value where 0 indicates female and 1 indicates male. Missing entries are not currently supported.

MotherID

A numeric value representing the unique identifier for an individual's mother.

FatherID

A numeric value representing the unique identifier for an individual's father.

isProband

A numeric value where 1 indicates the individual is a proband and 0 otherwise.

CurAge

A numeric value indicating the age of censoring (current age if the person is alive or age at death if the person is deceased). Allowed ages range from 1 to 94.

isAff

A numeric value indicating the affection status of cancer, with 1 for diagnosed individuals and 0 otherwise. Missing entries are not supported.

Age

A numeric value indicating the age of cancer diagnosis, encoded as NA if the individual was not diagnosed. Allowed ages range from 1 to 94.

Geno

A column for germline testing or tumor marker testing results. Positive results should be coded as 1, negative results as 0, and unknown results as NA or left empty.

Source

Generated for package example

penetrance documentation built on April 4, 2025, 12:29 a.m.