trimDoses: Trim Dose Data Set

In pkdata: Creates Pharmacokinetic/Pharmacodynamic (PK/PD) Data

Description

Remove invalid doses by creating a time frame window constructed from drug level data.

Usage

trimDoses(
  doseData,
  drugLevelData,
  drugLevelID = "id",
  drugLevelTimeVar = "date.time",
  drugLevelVar = "fent.level",
  infusionDoseTimeVar = NULL,
  infusionDoseVar = NULL,
  bolusDoseTimeVar = NULL,
  bolusDoseVar = NULL,
  otherDoseTimeVar = NULL,
  otherDoseVar = NULL,
  lookForward = 7,
  last = NA
)

Arguments

doseData	data.frame; data set with dose information
drugLevelData	data.frame; data set with drug level data
drugLevelID	character string; name of ID variable, defaults to id
drugLevelTimeVar	character string; name of date-time variable, defaults to date.time
drugLevelVar	character string; name of drug level variable, defaults to fent.level
infusionDoseTimeVar	character string; name of infusion dose time variable
infusionDoseVar	character string; name of infusion dose variable
bolusDoseTimeVar	character string; name of bolus dose time variable
bolusDoseVar	character string; name of bolus dose variable
otherDoseTimeVar	character string; name of additional dose time variable
otherDoseVar	character string; name of additional dose variable
lookForward	integer; initializes the time frame window with the number of days prior to the first drug level data; defaults to 7
last	integer; sets the end of the time frame window to be "last" days after the first dose date, rather than the date of the last drug level data

Details

The time frame window is generally seven days before drug level data up through the last drug level data record. The window can be adjusted by setting the lookForward and last arguments.

Value

data.frame, containing trimmed dose data

Author(s)

Cole Beck

pkdata documentation built on Oct. 23, 2020, 6:19 p.m.