scale_enzymatic: Scale clearance by age for when enzymatic clearance is known...

Description Usage Arguments

View source: R/IVIVEScaling.R

Description

Scale clearance by age for when enzymatic clearance is known at reference age.

Usage

1
scale_enzymatic(out_ages, tot_scaled_recomcl, cypDb, cypCl, gender)

Arguments

out_ages

out_ages Ages for which the clearance needs to be calculated including reference age

tot_scaled_recomcl

Total Recombinant enzyme clearance at reference age in L/h/kg Liver

cypDb

Dataframe containing cyp datasets to scale measured clearance values from in-vitro to in-vivo

cypCl

Datafarame containing measured invitro enzymatic clearance.

gender

Gender, either "M" for male or "F" for female. Needed to get Liver weight


plethem documentation built on Nov. 8, 2020, 4:35 p.m.