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pocrm: Dose Finding in Drug Combination Phase I Trials Using PO-CRM
Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) <doi:10.1177/1740774511408748> for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.
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Package details |
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| Author | Nolan A. Wages |
| Maintainer | "Brewer, Ben (arb5mt)" <arb5mt@virginia.edu> |
| License | GPL-2 |
| Version | 0.13 |
| Package repository | View on CRAN |
| Installation |
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