pocrm: Dose Finding in Drug Combination Phase I Trials Using PO-CRM

Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.

Author
Nolan A. Wages
Date of publication
2015-04-10 01:31:10
Maintainer
"Varhegyi, Nikole (nev4g)" <nev4g@eservices.virginia.edu>
License
GPL-2
Version
0.9

View on CRAN

Man pages

getwm
Obtain the working models for use in the partial order...
pocrm.imp
Executing the PO-CRM
pocrm.sim
Simulating the PO-CRM

Files in this package

pocrm
pocrm/NAMESPACE
pocrm/R
pocrm/R/pocrm.sim.R
pocrm/R/getwm.R
pocrm/R/pocrm.imp.R
pocrm/MD5
pocrm/DESCRIPTION
pocrm/man
pocrm/man/pocrm.imp.Rd
pocrm/man/getwm.Rd
pocrm/man/pocrm.sim.Rd