noFalseCalls: Function to calculate the number of false calls for a design...

Description Usage Arguments Value Author(s)

Description

This is an internal function. Please use cautiously if calling directly. Returns the number of false calls from a simulation study exploring the impact of varying PDXn and PDXr for an underlying Biol_RR for a particularly go-no go threshold. A false call can only arise in the situation where the underlying Biol_RR is below the go-no go threshold. Example usage: noFalseCalls(ImpactVarying_PDXn_PDXr_BRR, GoNoGoThreshold=30)

Usage

1
noFalseCalls(dataset, GoNoGoThreshold)

Arguments

dataset

dataset obtained as output from the 'varying_PDXn_PDXr' function

GoNoGoThreshold

go-no go threshold

Value

vector with three elements:

- numeric value indicating the number of experiments simulated

- numeric value indicating the number of experiments which were above the go-no go threshold

- numeric value indicating the FPR

Author(s)

Maria Luisa Guerriero, maria.guerriero@astrazeneca.com

Natasha A. Karp, natasha.karp@astrazeneca.com


populationPDXdesign documentation built on May 2, 2019, 9:13 a.m.