pro: Point-Process Response Model for Optogenetics

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Optogenetics is a new tool to study neuronal circuits that have been genetically modified to allow stimulation by flashes of light. This package implements the methodological framework, Point-process Response model for Optogenetics (PRO), for analyzing data from these experiments. This method provides explicit nonlinear transformations to link the flash point-process with the spiking point-process. Such response functions can be used to provide important and interpretable scientific insights into the properties of the biophysical process that governs neural spiking in response to optogenetic stimulation.

Author
Xi (Rossi) LUO with contributions from Dylan Small and Vikaas Sohal
Date of publication
2015-09-17 22:50:12
Maintainer
Xi (Rossi) LUO <xi.rossi.luo@gmail.com>
License
GPL-2
Version
0.1.1

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Man pages

model.pro
Model matrix for point-process responses
pro
Fit the PRO model
sim.lif
Simulate optogenetic stimulation on a leaky-integrate-fire...

Files in this package

pro
pro/NAMESPACE
pro/R
pro/R/pro.R
pro/R/model.pro.R
pro/R/sim.lif.R
pro/MD5
pro/DESCRIPTION
pro/ChangeLog
pro/man
pro/man/model.pro.Rd
pro/man/pro.Rd
pro/man/sim.lif.Rd