proteomicdesign: Optimization of a multi-stage proteomic study

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This package provides functions to identify the optimal solution that maximizes numbers of detectable differentiated proteins from a multi-stage clinical proteomic study.

Author
Irene SL Zeng
Date of publication
2013-01-04 12:04:40
Maintainer
Irene Zeng <zeng@stat.auckland.ac.nz>
License
GPL-3
Version
2.0

View on CRAN

Man pages

calculate.cost
Function to calculate the total cost of the multi-stage...
calculate.n3
A function to calculate the stage III sample size based on...
do.one.experiment
Simulation function for calculate the expected number of...
do.one.experiment.t
Simulation function for calculating the expected number of...
Ftest.Ttest
A function to perform the paired t test for each protein, and...
genseq.appr
A sub function to generate the sub solution space
genseq.group
A sub function to generate the sub solution space
genseq.single
A sub function to generate the sub solution space
optim.two.stage.appr
Optimize numbers of discoveries by using an approximated...
optim.two.stage.group
Optimization of the design parameters in the discovery ,...
optim.two.stage.single
Optimization of the number of discoveries from a multistage...
ots.env
assign the current working environment
power
The power function used in the optim.two.stage.single...
power.appr
The power function used in the optim.two.stage.appr function
power.group.cost
Derive the averaged estimated costs of stage II and III and...
power.single.cost
Derive the averaged estimated costs of stage II and III and...
power.t
The power function used in the optim.two.stage.single...
proteomic.optim.two.stage.v2.0-package
Optimization of a multi stage proteomic study
Ttest
The function to calculate the p values for each protein in...

Files in this package

proteomicdesign
proteomicdesign/MD5
proteomicdesign/R
proteomicdesign/R/power.single.cost.R
proteomicdesign/R/power.group.cost.R
proteomicdesign/R/optim.two.stage.single.R
proteomicdesign/R/optim.two.stage.group.R
proteomicdesign/R/optim.two.stage.appr.R
proteomicdesign/NAMESPACE
proteomicdesign/man
proteomicdesign/man/Ttest.Rd
proteomicdesign/man/proteomic.optim.two.stage.v2.0-package.Rd
proteomicdesign/man/power.t.Rd
proteomicdesign/man/power.single.cost.Rd
proteomicdesign/man/power.Rd
proteomicdesign/man/power.group.cost.Rd
proteomicdesign/man/power.appr.Rd
proteomicdesign/man/ots.env.Rd
proteomicdesign/man/optim.two.stage.single.Rd
proteomicdesign/man/optim.two.stage.group.Rd
proteomicdesign/man/optim.two.stage.appr.Rd
proteomicdesign/man/genseq.single.Rd
proteomicdesign/man/genseq.group.Rd
proteomicdesign/man/genseq.appr.Rd
proteomicdesign/man/Ftest.Ttest.Rd
proteomicdesign/man/do.one.experiment.t.Rd
proteomicdesign/man/do.one.experiment.Rd
proteomicdesign/man/calculate.n3.Rd
proteomicdesign/man/calculate.cost.Rd
proteomicdesign/DESCRIPTION