potency_weights_from_reference_doses: Derive relative potency weights from reference doses

In qtbi: Quantum Toxic Burden Index

Derive relative potency weights from reference doses

Description

Computes outcome-independent weights as the ratio of the index chemical reference dose to each component reference dose:

w_i = \mathrm{RfD}_{\mathrm{index}} / \mathrm{RfD}_i

Usage

potency_weights_from_reference_doses(
  reference_doses,
  chemicals,
  reference_index = NULL
)

Arguments

reference_doses	Named numeric vector of oral reference doses in mg/kg/day, with one value per exposure in chemicals.
chemicals	Character vector of exposure identifiers in panel order. Names must match names(reference_doses).
reference_index	Name of the index chemical. Defaults to the first entry in chemicals.

Details

Lower reference doses (more potent toxicants) receive larger weights.

Value

Named numeric vector of potency weights aligned with chemicals.

qtbi documentation built on June 9, 2026, 5:09 p.m.