rCRM: Regularized Continual Reassessment Method

Fit a 2-parameter continual reassessment method (CRM) model (O'Quigley and Shen (1996), <doi: 10.2307/2532905>) regularized with L2 norm (Friedman et al. (2010), <doi: 10.18637/jss.v033.i01>) adjusted by the distance with the target dose limiting toxicity (DLT) rate.

Package details

AuthorXiang Li, Hong Tian, Kevin Liu, Pilar Lim
MaintainerXiang Li <xli256@its.jnj.com>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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rCRM documentation built on Oct. 23, 2020, 5:54 p.m.