To discover the associations between SNPs and Crohn's disease, 635547 SNPs were examined in a primary study. For follow-up, 126 SNPs were measured in an independent study. The criteria for follow-up were as follows: the two smallest p-values in each distinct region with primary study p-values below 0.00005.
A data frame with 126 rows and 3 columns:
||integer||just the row number.|
||numeric||p-value from study 1.|
||numeric||p-value from study 2.|
Barrett, Jeffrey C., et al. "Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease." Nature genetics 40.8 (2008): 955.
Bogomolov, M. and Heller, R. (2013). Discovering findings that replicate from a primary study of high dimension to a follow-up study. Journal of the American Statistical Association, Vol. 108, No. 504, Pp. 1480-1492.
the example in
radjust_pf uses this data.
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