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Data from two genome-wide association studies for protenomics and the internal lung cancer consortium study. The outcome is the squamous cell lung cancer, and the exposures are interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist.
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An matrix contains the genetic associations of the exposures and the outcome.
1. Sun et al. (2018) Genomic atlas of the human plasma proteome. Nature, 558(7708):73-79
2. Ahola-Olli et al. (2017) Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors. Am J Hum Genet,100(1):40-50.
3. Wang et al. (2014) Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nat Genet, 46(7):736-41.
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