fibrosis: Fibrosis dataset

In sMSROC: Assessment of Diagnostic and Prognostic Markers

Fibrosis dataset

Description

Synthetic dataset generated to simulate data from a study that aimed to assess the predictive ability of a constructed score to determine the worsening in the fibrosis stage in individuals infected by the hepatitis C (HC) virus. When participants underwent a target revision, their fibrosis stage, certain polymorphisms, and other clinical variables were collected. Highest stages of fibrosis were considered a worsening in the disease. See References for more information about the study.

Usage

data("fibrosis")

Format

A data frame with 722 observations and the following variables:

Id

Identification label for each participant.

Score

Score proposed to stratify participants infected by the HC virus according to the risk of a worsening in their fibrosis stage.

Start

Lower edge of the observable interval.

Stop

Upper edge of the observable interval. It can take the value infinity, represented as Inf.

Source

Synthetic dataset.

References

Vidal-Castineira JR. al. Genetic contribution of endoplasmic reticulum aminopeptidase 1 polymorphisms to liver fibrosis progression in patients with HCV infection. Journal of Molecular Medicine, 98:1245-1254, 2020. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1007/s00109-020-01948-1")}

Examples

data(fibrosis)
summary(fibrosis)

sMSROC documentation built on May 29, 2024, 1:43 a.m.