LRneg: Sample Size for Estimating LR negative of a Single Diagnostic...

In samplesizeestimator: Calculate Sample Size for Various Scenarios

Sample Size for Estimating LR negative of a Single Diagnostic Test

Description

Calculate sample size(cases) based on negative likelihood ratio an unified index for comparing the accuracy of two diagnostic tests

Usage

LRneg(se, sp, lrneg, alp, pwr, k = 1)

Arguments

se	anticipated sensitivity of the diagnostic test
sp	anticipated specificity of the diagnostic test
lrneg	anticipated LR negative value
alp	level of significance
pwr	desired level of power
k	number of control(s) per case

Value

a list object with minimum required sample size with reporting

Author(s)

R. Amala, Scientist-C, ICMR-VCRC, Puducherry & G. Kumarapandiyan, Asst. Prof., Madras Christian College, Chennai

References

Simel, D.L., Samsa, G.P. Matchar, D. B. (1991). Likelihood ratio with confidence: sample size estimation for diagnostic test studies. J Clin Epidemiol. 44: 763-70.

Examples

LRneg(se=0.9, sp=0.5,lrneg=0.4,alp=0.05, pwr=0.8,k=1)

samplesizeestimator documentation built on Oct. 11, 2023, 1:06 a.m.