nutrimouse: Nutrimouse dataset

In seedCCA: Seeded Canonical Correlation Analysis

Nutrimouse dataset

Description

The nutrimouse dataset comes from a nutrition study in the mouse. It was provided by Pascal Martin from the Toxicology and Pharmacology Laboratory (French National Institute for Agronomic Research).

Usage

data(nutrimouse)

Format

gene: data frame (40 * 120) with numerical variables

lipid: data frame (40 * 21) with numerical variables

diet: factor vector (40)

genotype: factor vector (40)

Details

Two sets of variables were measured on 40 mice:

expressions of 120 genes potentially involved in nutritional problems.

concentrations of 21 hepatic fatty acids: The 40 mice were distributed in a 2-factors experimental design (4 replicates).

Genotype (2-levels factor): wild-type and PPARalpha -/-

Diet (5-levels factor): Oils used for experimental diets preparation were corn and colza oils (50/50) for a reference diet (REF), hydrogenated coconut oil for a saturated fatty acid diet (COC), sunflower oil for an Omega6 fatty acid-rich diet (SUN), linseed oil for an Omega3-rich diet (LIN) and corn/colza/enriched fish oils for the FISH diet (43/43/14).

References

P. Martin, H. Guillou, F. Lasserre, S. D??jean, A. Lan, J-M. Pascussi, M. San Cristobal, P. Legrand, P. Besse, T. Pineau (2007) Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study. Hepatology, 45, 767???777

Examples

data(nutrimouse)
boxplot(nutrimouse$lipid)

seedCCA documentation built on June 9, 2022, 9:05 a.m.