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An implementation of the full-likelihood Bayes factor (FLB) for evaluating segregation evidence in clinical medical genetics. The method was introduced by Thompson et al. (2003) <doi:10.1086/378100>, and further popularised by Bayrak-Toydemir et al. (2008) <doi:10.1016/j.yexmp.2008.03.006>. This implementation allows custom penetrance values and liability classes, and includes specialised pedigree visualisations.
Package details |
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Author | Magnus Dehli Vigeland [aut, cre] (<https://orcid.org/0000-0002-9134-4962>), Christian Carrizosa [aut] (<https://orcid.org/0000-0002-3919-0011>) |
Maintainer | Magnus Dehli Vigeland <m.d.vigeland@medisin.uio.no> |
License | GPL-3 |
Version | 0.3.0 |
URL | https://github.com/magnusdv/segregatr |
Package repository | View on CRAN |
Installation |
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