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speff2trial: Semiparametric Efficient Estimation for a Two-Sample Treatment Effect
Performs estimation and testing of the treatment effect in a 2-group randomized clinical trial with a quantitative, dichotomous, or right-censored time-to-event endpoint. The method improves efficiency by leveraging baseline predictors of the endpoint. The inverse probability weighting technique of Robins, Rotnitzky, and Zhao (JASA, 1994) is used to provide unbiased estimation when the endpoint is missing at random.
Getting started
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Package details |
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| Author | Michal Juraska <mjuraska@fredhutch.org>, with contributions from Peter B. Gilbert <pgilbert@scharp.org>, Xiaomin Lu <xlu2@phhp.ufl.edu>, Min Zhang <mzhangst@umich.edu>, Marie Davidian <davidian@stat.ncsu.edu>, and Anastasios A. Tsiatis <tsiatis@stat.ncsu.edu> |
| Maintainer | Michal Juraska <mjuraska@fredhutch.org> |
| License | GPL-2 |
| Version | 1.0.5 |
| URL | https://github.com/mjuraska/speff2trial |
| Package repository | View on CRAN |
| Installation |
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