speff2trial: Semiparametric efficient estimation for a two-sample treatment effect

The package performs estimation and testing of the treatment effect in a 2-group randomized clinical trial with a quantitative, dichotomous, or right-censored time-to-event endpoint. The method improves efficiency by leveraging baseline predictors of the endpoint. The inverse probability weighting technique of Robins, Rotnitzky, and Zhao (JASA, 1994) is used to provide unbiased estimation when the endpoint is missing at random.

Getting started

Package details

AuthorMichal Juraska <[email protected]>, with contributions from Peter B. Gilbert <[email protected]>, Xiaomin Lu <[email protected]>, Min Zhang <[email protected]>, Marie Davidian <[email protected]>, and Anastasios A. Tsiatis <[email protected]>
MaintainerMichal Juraska <[email protected]>
Package repositoryView on CRAN
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speff2trial documentation built on May 1, 2019, 9:51 p.m.