speff2trial: Semiparametric efficient estimation for a two-sample treatment effect

The package performs estimation and testing of the treatment effect in a 2-group randomized clinical trial with a quantitative, dichotomous, or right-censored time-to-event endpoint. The method improves efficiency by leveraging baseline predictors of the endpoint. The inverse probability weighting technique of Robins, Rotnitzky, and Zhao (JASA, 1994) is used to provide unbiased estimation when the endpoint is missing at random.

Author
Michal Juraska <mjuraska@u.washington.edu>, with contributions from Peter B. Gilbert <pgilbert@scharp.org>, Xiaomin Lu <xlu2@phhp.ufl.edu>, Min Zhang <mzhangst@umich.edu>, Marie Davidian <davidian@stat.ncsu.edu>, and Anastasios A. Tsiatis <tsiatis@stat.ncsu.edu>
Date of publication
2012-10-30 19:58:36
Maintainer
Michal Juraska <mjuraska@u.washington.edu>
License
GPL-2
Version
1.0.4

View on CRAN

Man pages

ACTG175
AIDS Clinical Trials Group Study 175
modSearch
Internal function for speff()
speff
Semiparametric efficient estimation and testing for a...
speffSurv
Semiparametric efficient estimation and testing for a...
summaryspeff
Summarizing results for semiparametric efficient estimation...
summaryspeffSurv
Summarizing results for semiparametric efficient estimation...

Files in this package

speff2trial
speff2trial/MD5
speff2trial/man
speff2trial/man/speff.Rd
speff2trial/man/ACTG175.Rd
speff2trial/man/summaryspeff.Rd
speff2trial/man/summaryspeffSurv.Rd
speff2trial/man/speffSurv.Rd
speff2trial/man/modSearch.Rd
speff2trial/NAMESPACE
speff2trial/R
speff2trial/R/speff.R
speff2trial/R/modSearch.R
speff2trial/R/summary.speff.R
speff2trial/R/summary.speffSurv.R
speff2trial/R/print.summary.speffSurv.R
speff2trial/R/speffSurv.R
speff2trial/R/print.summary.speff.R
speff2trial/data
speff2trial/data/ACTG175.txt.gz
speff2trial/DESCRIPTION