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ssutil: Sample Size Calculation Tools
Functions for sample size estimation and simulation in clinical trials. Includes methods for selecting the best group using the Indifference-zone approach, as well as designs for non-inferiority, equivalence, and negative binomial models. For the sample size calculation for non-inferiority of vaccines, the approach is based on Fleming, Powers, and Huang (2021) <doi:10.1177/1740774520988244>. The Indifference-zone approach is based on Sobel and Huyett (1957) <doi:10.1002/j.1538-7305.1957.tb02411.x> and Bechhofer, Santner, and Goldsman (1995, ISBN:978-0-471-57427-9).
Getting started
Package overview
README.md
Equivalence Testing for Normal Outcomes
Power for rare events
Selecting the best group using the Indifference-Zone approach for binomial outcomes
Selecting the best group using the Indifference-Zone approach for normal outcomes
Simulations for Negative Binomial outcomes
Simulations for Non-inferiority trials
Browse package contents
Package details |
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| Author | John J. Aponte [aut, cre] (ORCID: <https://orcid.org/0000-0002-3014-3673>), Chris Gast [ctb] |
| Maintainer | John J. Aponte <john.j.aponte@gmail.com> |
| License | AGPL (>= 3) |
| Version | 1.2.0 |
| URL | https://johnaponte.github.io/ssutil/ https://github.com/johnaponte/ssutil |
| Package repository | View on CRAN |
| Installation |
Install the latest version of this package by entering the following in R:
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