Description Details Author(s) References See Also
The stress addition approach is an alternative to the traditional concentration addition or effect addition models. It allows the modelling of tri-phasic concentration-response relationships either as single toxicant experiments, in combination with an environmental stressor or as mixtures of two toxicants. See Liess et al. (2019) <doi:10.1038/s41598-019-51645-4> and Liess et al. (2020) <doi:10.1186/s12302-020-00394-7>.
This R package contains the definitions of the ECx-SyS model and the Multi-TOX model. See the publications linked below for more information including equations.
Author contributions: M. Liess conceived the ECx-SyS and Multi-TOX models. S. Henz developed this R package. N. Shahid contributed to the optimization of the Multi-TOX model and provided the multiple_stress data set.
Maintainer: Sebastian Henz bastihz.dev@posteo.de (ORCID)
Authors:
Matthias Liess (ORCID)
Other contributors:
Naeem Shahid (ORCID) [contributor]
Helmholtz-Zentrum fuer Umweltforschung GmbH - UFZ [copyright holder, funder]
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