subgxe: Combine Multiple GWAS by Using Gene-Environment Interactions

Classical methods for combining summary data from genome-wide association studies (GWAS) only use marginal genetic effects and power can be compromised in the presence of heterogeneity. 'subgxe' is a R package that implements p-value assisted subset testing for association (pASTA), a method developed by Yu et al. (2019) <doi:10.1159/000496867>. pASTA generalizes association analysis based on subsets by incorporating gene-environment interactions into the testing procedure.

Package details

AuthorYoufei Yu [aut], Alexander Rix [cre]
MaintainerAlexander Rix <[email protected]>
Package repositoryView on CRAN
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subgxe documentation built on June 14, 2019, 5:05 p.m.