subtee: Subgroup Treatment Effect Estimation in Clinical Trials

Naive and adjusted treatment effect estimation for subgroups. Model averaging (Bornkamp, 2016 <doi:10.1002/pst.1796>) and bagging (Rosenkranz, 2016 <doi:10.1002/bimj.201500147>) are proposed to address the problem of selection bias in treatment effect estimates for subgroups. The package can be used for all commonly encountered type of outcomes in clinical trials (continuous, binary, survival, count). Additional functions are provided to build the subgroup variables to be used and to plot the results using forest plots.

Package details

AuthorNicolas Ballarini [aut, cre], Bjoern Bornkamp [aut], Marius Thomas [aut, cre], Baldur Magnusson [ctb]
MaintainerNicolas Ballarini <>
Package repositoryView on CRAN
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subtee documentation built on May 2, 2019, 9:23 a.m.