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#' PRIME data set
#'
#' This data set is from a longitudinal study called "Prospective Research in Memory Clinics" (PRIME),
#' see Brodaty et al (2011), with a period of 3-year. The data set includes 583 dementia patients. The
#' outcome is time to institutionalised. The predicators are age, sex, educational level, living status,
#' dementia type, baseline cognitive ability (MMSE), baseline functional ability (SMAF),
#' baseline neuropsychiatric symptoms (total NPI), baseline dementia severity (CDR),
#' baseline caregiver burden (ZBI), medication types, change in cognitive ability at 3 months,
#' change in functional ability at 3 months, and change in neuropsychiatric symptoms at 3 months.
#' Note that this data set is complete and was analyzed by Brodaty et al (2014).
#'
#' @name PRIME
#' @format A data frame with 583 observations on 18 variables.
#' \describe{
#' \item{Time}{observed time in term of months}
#' \item{Event}{event or institutionalisation, 1=Yes and 0=No}
#' \item{Depcen}{dependent right censoring or withdrawal, 1=Yes and 0=No}
#' \item{Age}{age at baseline, 1=80 years or above and 0=80 year below}
#' \item{Gender}{gender, 1=Female and 0=Male}
#' \item{HighEdu}{education level at baseline, 1=high school above and 0=high school
#' or below}
#' \item{Alzheimer}{Alzheimer disease, 1=Yes and 0=No}
#' \item{CDR_base}{dementia severity at baseline}
#' \item{MMSE_base}{cognitive ability at baseline}
#' \item{SMAF_base}{functional ability at baseline}
#' \item{ZBI_base}{caregiver burden at baseline}
#' \item{NPI_base}{neuropsychiatric symptoms at baseline}
#' \item{Benzon}{benzodiazepines taking, 1=Yes and 0=No}
#' \item{Antiphsy}{anti-psychotics taking, 1=Yes and 0=No}
#' \item{LivingAlone}{living alone, 1=Yes and 0=No}
#' \item{MMSE_change_3m}{cognitive ability change at 3-month from baseline}
#' \item{SMAF_change_3m}{functional ability change at 3-month from baseline}
#' \item{NPI_change_3m}{neuropsychiatric symptoms change at 3-month from baseline}
#' }
#'
#' @docType data
#' @keywords datasets
#' @usage data(PRIME)
#' @references
#' Brodaty H, Woodward M, Boundy K, Ames D, Balshaw R. (2011). \emph{"Patients in Australian memory clinics:
#' baseline characteristics and predictors of decline at six months"}. Int Psychogeriatr 23, 1086-1096.
#'
#' Brodaty H, Connors M, Xu J, Woodward M, Ames D. (2014). \emph{"Predictors of institutionalization
#' in dementia: a three year longitudinal study"}. Journal of Alzheimers Disease 40, 221-226.
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