Trigger Strategy in Clinical Trials

alpha2boundary | Convert cumulative alpha levels to normal critical boundaries |

boundary2alpha | Convert normal critical boundaries to cumulative alpha... |

corrMatGenerator | Correlation matrix generator |

gbounds | Critical boundary in group sequential trials |

marginalPwR | Marginal Power Rate |

psPwRbhmb | Powers of testing the primary and secondary hypotheses |

psPwRtrigger | Powers of testing the primary and secondary hypotheses using... |

sBoundsPh2 | Critical boundaries for the secondary endpoint in the... |

sErrRphInt2 | Type I error rate of the overall null hypothesis using the... |

solveAlphaXsampleSize | Sample size calculation |

solveAlphaXsampleSizeGA | Sample size calculation using Genetic Algorithms |

sPwRholm | Power of testing the secondary hypothesis using Holm |

sPwRholmye | Power of testing the secondary hypothesis using Holm-Ye |

sPwRnaiveBonf | Power of testing the secondary hypothesis using Bonferroni |

sPwRph2 | Power of testing the secondary hypothesis in partially... |

sPwRtrigger | Power of testing the secondary hypothesis using Trigger... |

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