tsdf: Two-/Three-Stage Designs for Phase 1&2 Clinical Trials

Calculates Zhong's optimal two-/three-stage Phase II designs for single-arm trials, generates target-toxicity decision tables for two-/three-stage Phase I dose-finding, and supports dose-finding simulations using custom decision tables. The Phase II design is based on Zhong (2012) <doi:10.1016/j.cct.2012.07.006>.

Package details

AuthorWenchuan Guo [aut, cre], Jianan Hui [aut], Bob Zhong [aut]
MaintainerWenchuan Guo <wguo1017@gmail.com>
LicenseGPL-2
Version1.1-9
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("tsdf")

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tsdf documentation built on April 26, 2026, 1:06 a.m.