valorate: Velocity and Accuracy of the LOg-RAnk TEst

The algorithm implemented in this package was designed to quickly estimates the distribution of the log-rank especially for heavy unbalanced groups. VALORATE estimates the null distribution and the p-value of the log-rank test based on a recent formulation. For a given number of alterations that define the size of survival groups, the estimation involves a weighted sum of distributions that are conditional on a co-occurrence term where mutations and events are both present. The estimation of conditional distributions is quite fast allowing the analysis of large datasets in few minutes <http://bioinformatica.mty.itesm.mx/valorate>.

AuthorVictor Trevino [aut, cre]
Date of publication2016-10-09 23:23:03
MaintainerVictor Trevino <vtrevino@itesm.mx>
LicenseGPL (>= 2)
Version1.0-1
http://bioinformatica.mty.itesm.mx/valorate

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