The algorithm implemented in this package was
designed to quickly estimates the distribution of the
log-rank especially for heavy unbalanced groups. VALORATE
estimates the null distribution and the p-value of the
log-rank test based on a recent formulation. For a given
number of alterations that define the size of survival
groups, the estimation involves a weighted sum of
distributions that are conditional on a co-occurrence term
where mutations and events are both present. The estimation
of conditional distributions is quite fast allowing the
analysis of large datasets in few minutes
|Author||Victor Trevino [aut, cre]|
|Date of publication||2016-10-09 23:23:03|
|Maintainer||Victor Trevino <[email protected]>|
|License||GPL (>= 2)|
|Package repository||View on CRAN|
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