The algorithm implemented in this package was designed to quickly estimates the distribution of the logrank especially for heavy unbalanced groups. VALORATE estimates the null distribution and the pvalue of the logrank test based on a recent formulation. For a given number of alterations that define the size of survival groups, the estimation involves a weighted sum of distributions that are conditional on a cooccurrence term where mutations and events are both present. The estimation of conditional distributions is quite fast allowing the analysis of large datasets in few minutes <http://bioinformatica.mty.itesm.mx/valorate>.
Package details 


Author  Victor Trevino [aut, cre] 
Maintainer  Victor Trevino <[email protected]> 
License  GPL (>= 2) 
Version  1.01 
URL  http://bioinformatica.mty.itesm.mx/valorate 
Package repository  View on CRAN 
Installation 
Install the latest version of this package by entering the following in R:

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