valytics-package: valytics: Statistical Methods for Analytical Method...

In valytics: Statistical Methods for Analytical Method Comparison and Validation

valytics: Statistical Methods for Analytical Method Comparison and Validation

Description

Provides statistical methods for analytical method comparison and validation studies. Implements Bland-Altman analysis for assessing agreement between measurement methods (Bland & Altman (1986) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1016/S0140-6736(86)90837-8")}), Passing-Bablok regression for non-parametric method comparison (Passing & Bablok (1983) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1515/cclm.1983.21.11.709")}), and Deming regression accounting for measurement error in both variables (Linnet (1993) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1093/clinchem/39.3.424")}). Also includes tools for setting quality goals based on biological variation (Fraser & Petersen (1993) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1093/clinchem/39.7.1447")}) and calculating Six Sigma metrics, precision experiments with variance component analysis, precision profiles for functional sensitivity estimation (Kroll & Emancipator (1993) https://pubmed.ncbi.nlm.nih.gov/8448849/). Commonly used in clinical laboratory method validation. Provides publication-ready plots and comprehensive statistical summaries.

Author(s)

Maintainer: Marcello Grassi [e-mail] (ORCID)

See Also

Useful links:

• https://github.com/marcellogr/valytics

• Report bugs at https://github.com/marcellogr/valytics/issues

valytics documentation built on Feb. 19, 2026, 5:06 p.m.