stress: Gene expression signatures of stress
In 3inar/geneset: Some gene sets and functions for working with them

Description Usage Format Source See Also Examples

A dataset containing 15 gene sets thought to be predictors of stress from the following studies:

Kuebler et al., 2015: One gene set
Powell et al., 2013: Two gene sets
Antoni et al., 2012: Four gene sets
Kawai et al., 2007: Seven gene sets
Morita et al., 2005: One gene set

For details, see sources below, as well as stress$names and stress$descriptions.

stress

A gset object.

U. Kuebler, C. Zuccarella-Hackl, A. Arpagaus, J. M. Wolf, F. Farahmand, R. von Känel, U. Ehlert, and P. H. Wirtz, “Stress-induced modulation of NF-κB activation, inflammation-associated gene expression, and cytokine levels in blood of healthy men,” Brain. Behav. Immun., vol. 46, pp. 87–95, 2015.

N. D. Powell, E. K. Sloan, M. T. Bailey, J. M. G. Arevalo, G. E. Miller, E. Chen, M. S. Kobor, B. F. Reader, J. F. Sheridan, and S. W. Cole, “Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis.,” Proc. Natl. Acad. Sci. U. S. A., vol. 110, no. 41, pp. 16574–9, Oct. 2013.

M. H. Antoni, S. K. Lutgendorf, B. Blomberg, C. S. Carver, S. Lechner, A. Diaz, J. Stagl, J. M. G. Arevalo, and S. W. Cole, “Cognitive-Behavioral Stress Management Reverses Anxiety-Related Leukocyte Transcriptional Dynamics,” Biol. Psychiatry, vol. 71, no. 4, pp. 366–372, 2012.

T. Kawai, K. Morita, K. Masuda, K. Nishida, M. Shikishima, M. Ohta, T. Saito, and K. Rokutan, “Gene expression signature in peripheral blood cells from medical students exposed to chronic psychological stress.,” Biol. Psychol., vol. 76, no. 3, pp. 147–55, Oct. 2007.

K. Morita, T. Saito, M. Ohta, T. Ohmori, K. Kawai, S. Teshima-Kondo, and K. Rokutan, “Expression analysis of psychological stress-associated genes in peripheral blood leukocytes.,” Neurosci. Lett., vol. 381, no. 1–2, pp. 57–62, 2005.

gset