boeal: Number of nalidixic acid-resistant mutants from Boe et al....

In AdriMaz/flan: FLuctuation ANalysis on Mutation Models

Number of nalidixic acid-resistant mutants from Boe et al. (1994)

Description

Samples from Table 4 p. 2784-2785 of Boe and al (1994).

Plates with more than 512 mutants could not be counted with precision, hence the value 512 must be understood as “512 or more”.

Usage

  data(boeal)

Format

A list of 23 samples of mutants counts, each named "B<index of the sample>".

The i-th sample of the list includes the i-th column of the table.

Source

L. Boe, T. Tolker-Nielsen, K. M. Eegholm, H. Spliid, and A. Vrang: Fluctuation analysis of mutations to nalidixic acid resistance in Escherichia Coli, J. Bacteriol., 176(10):2781-2787 (1994)

Examples

b <- unlist(boeal)              # concatenate all samples
ml <- mutestim(b)               # maximum likelihood
gf <- mutestim(b,method="GF")   # generating function
p0 <- mutestim(b,method="P0")   # P0 method
cbind(ml,gf,p0)                 # compare 3 methods

                                # test values of mutations and fitness
flan.test(b,alternative=c("greater","less"),mutations0=0.6,fitness0=1)

b1 <- unlist(boeal[1:10])       # first 10 samples
b2 <- unlist(boeal[11:20])      # next 10 samples
flan.test(list(b1,b2))          # test equality

AdriMaz/flan documentation built on Feb. 8, 2024, 9 p.m.