Description Usage Arguments Value
Identifies gene sets with a similar a prior defined profile using any combination of three feature or data types
1 | GISPA(feature,f.sets,g.set,ref.samp.idx,comp.samp.idx,f.profiles,cpt.data,cpt.method,cpt.max)
|
feature |
: Analysis type i.e., one ('1'), two ('2') or three ('3') dimensional feature analysis. |
f.sets |
: A list of ExpressionSet data objects corrosponding to a data type |
g.set |
: A GeneSet from an ExpressionSet to subset the f.sets for analysis purposes. 'geneIds' should corrospond to the gene names. Default is null, i.e., genome-wide analysis |
ref.samp.idx |
: Reference sample column index on which to determine the gene set profile. The default is 3 |
comp.samp.idx |
: The other two relative sample column index against which the profile is being determined. The default is 4 and 5 |
f.profiles |
: A vector of the desired direction of genomic change (or profile) corrosponding to each data type. The values are "up" or "down" for increased and decreased gene set profile, respectively |
cpt.data |
: Identify changepoints for data using variance (cpt.var), mean (cpt.mean) or both (meanvar). Default is cpt.var. |
cpt.method |
: Choice of single or multiple changepoint model. Default is "BinSeg". |
cpt.max |
: The maximum number of changepoints to search for using "BinSeg" method. Default is 60. This number is dependent on the number of input data points |
The returned value is a data matrix including the original data along with between gene profile statistics and identified changepoints.
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