README.md

In Codezy99/cliProfiler: A package for the CLIP data visualization

cliProfiler

Author: You Zhou, Kathi Zarnack

Introduction

Cross-linking immunoprecipitation (CLIP) is a technique that combines UV cross-linking and immunoprecipitation to analyse protein-RNA interactions or to pinpoint RNA modifications (e.g. m6A). CLIP-based methods, such as iCLIP and eCLIP, allow precise mapping of RNA modification sites or RNA-binding protein (RBP) binding sites on a genome-wide scale. These techniques help us to unravel post-transcriptional regulatory networks. In order to make the visualization of CLIP data easier, we develop r Biocpkg("cliProfiler") package. The r Biocpkg("cliProfiler") includes seven functions which allow users easily make different profile plots.

The r Biocpkg("cliProfiler") package is available at https://bioconductor.org and can be installed via BiocManager::install:

```{r BiocManager, eval=FALSE} if (!require("BiocManager")) install.packages("BiocManager") BiocManager::install("cliProfiler")

A package only needs to be installed once. Load the package into an
R session with

```{r initialize, results="hide", warning=FALSE, message=FALSE}
library(cliProfiler)

How to use it

Documentation (vignette and user manual) is available at the cliProfiler Bioconductor landing page at http://bioconductor.org/packages/cliProfiler.

Codezy99/cliProfiler documentation built on Dec. 17, 2021, 2:59 p.m.