glsdrm: Dose-response curve estimation by generalized least squares

In DoseResponse/medrc: Mixed effect dose-response curves

Description

Implements drc nonlinear functions into the nlme framework for nonlinear GLS dose-response modeling.

Usage

glsdrm(form, curveid = NULL, data, fct, correlation = NULL,
  weights = NULL, control = NULL, start = NULL)

Arguments

form	Formula describing the dose-response relationship
curveid	Formula with parameter names on the left hand side (divided by +) and a column name in data, denoting a factor, to estimate separate parameters per factor-level. If NULL only fixed effects for a single curve will be estimated.
data	a data.frame object
fct	a function of the drc package
correlation	additional corClasses object
weights	additional varClasses object
control	list with nlme control arguments
start	optional list with initial values for the fixed components. If NULL the initial values will be found automatically

Details

An application of glsdrm is shown on the help pages of data broccoli. EDx and selectivity indices can be calculated with functions ED and EDcomp. Model-averaged ED can be computed by function mmaED.

Value

An object of class glsdrc

See Also

drm, gls

DoseResponse/medrc documentation built on May 28, 2019, 12:36 p.m.