DudbridgeLab/AVENGEME: Analysis of polygenic scoring methods
AVENGEME (Additive Variance Explained and Number of Genetic Effects Method of Estimation) is a package for the analysis of the polygenic scoring method. Polygenic scores access a large proportion of the heritability of a trait by aggregating genetic effects across thousands of markers into a single composite score. The markers may not be individually associated with the trait at standard statistical significance levels. However, the composite score may be associated, indicating a substantial polygenic component within the score.
Getting started
Browse package contents
Package details |
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| Author | Frank Dudbridge [aut, cre] |
| Maintainer | Frank Dudbridge <frank.dudbridge@leicester.ac.uk> |
| License | GPL-3 |
| Version | 1.0 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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