| PRSdata | R Documentation |
Simulated liabilities and polygenic risk scores for six complex diseases, with corresponding disease outcomes and risk predictions.
PRSdata
A list with 7 elements. Each element is a matrix with 10,000 rows and 6 columns corresponding to simulated data on 10,000 individuals for 6 diseases. Diseases are modelled on type-2 diabetes, coronary artery disease, Crohn's disease, ulcerative colitis, schizophrenia and rheumatoid arthritis.
PRSPolygenic risk scores
liabilityLiabilities
riskDisease risks corresponding to PRS
diseaseDisease outcomes corresponding to liability
VLVariance-covariance matrix of liability
VXVariance-covariance matrix of PRS
h2Disease heritabilities
prevalenceDisease prevalences
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