linORscale | R Documentation |
Convert effect sizes and standard error from linear to log-odds scale
linORscale(beta, se, N0, N1)
beta |
a numeric vector of Beta in linear scale. |
se |
a numeric vector of SE in linear scale. |
N0 |
number of controls in the study. |
N1 |
number of cases in the study. |
Binary traits in case-control studies can be analysed by BOLT-LMM, which uses a linear model. This function provides an approximation from linear to log-odds scale for Beta and SE, as described in BOLT-LMM manual (https://data.broadinstitute.org/alkesgroup/BOLT-LMM/).
a list containing beta and se.beta in log-odds scale.
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