Description Details Author(s) References
The package performs single nucleotide polymorphism (SNP) missing value imputation for their next generation gene sequencing data without a reference genome. The tool should be able to predict the missing SNP value based on a certain number of SNPs around the missing point.
Read in vcf file time or raw sequencing files, and impute missing single SNP values. This package currently containing a few testing features that introduces additional missing positions to test different methods.
Main functions:
Impute_GenoType_XGBoost
Create_Single_SNP_Object
classfication_error
Generate_NA
vcf2df
Guannan Gao
Maintainer: Guannan Gao <gaog@stat.tamu.edu>
Kabisch, Maria, Ute Hamann, and Justo Lorenzo Bermejo. "Imputation of missing genotypes within LD-blocks relying on the basic coalescent and beyond: consideration of population growth and structure." BMC genomics 18.1 (2017): 798.
Tianqi Chen and Carlos Guestrin, "XGBoost: A Scalable Tree Boosting System", 22nd SIGKDD Conference on Knowledge Discovery and Data Mining, 2016, https://arxiv.org/abs/1603.02754
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