Description Author(s) See Also
This package contains functions to create a whole blood DNA-methylation based in utero exposure score to maternal smoking. This score was developed using elastic net regression. The weights provided here can be applied to Illumina HumanMethylation450 or EPIC array data. The output can both be a score or a binary classification. This package contains both the function necessary for the score calculation and the weights for the CpGs required for the calculation. Further, it contains a shiny app to create the score and compare the results against available information of exposure to maternal smoking in the user's cohort.
Maintainer: Sebastian Rauschert Sebastian.Rauschert@telethonkids.org.au
Useful links:
Report bugs at https://github.com/Hobbeist/DNAsmokeR/issues
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