IgDAWG/BIGDAWG: Case-Cotrol Analysis of Multi-Allelic Loci
Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.
Getting started
Browse package contents
Package details |
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| Author | Derek Pappas <djpappas75@gmail.com>, Steve Mack <Steven.Mack@ucsf.edu>, Jill Hollenbach <Jill.Hollenbach@ucsf.edu> |
| Maintainer | Steve Mack <Steven.Mack@ucsf.edu> |
| License | GPL (>= 3) |
| Version | 3.0.8 |
| URL | http://tools.immunogenomics.org/ https://github.com/IgDAWG/BIGDAWG |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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