IntiQuan/NonCompartIQR: Supportive functions for NCA

Conduct a noncompartmental analysis as closely as possible to the most widely used commercial software for pharmacokinetic analysis, i.e. 'Phoenix(R) WinNonlin(R)' <https://www.certara.com/software/pkpd-modeling-and-simulation/phoenix-winnonlin/>. Some features are 1) Use of CDISC SDTM terms 2) Automatic slope selection with the same criterion of WinNonlin(R) 3) Supporting both 'linear-up linear-down' and 'linear-up log-down' method 4) Interval(partial) AUCs with 'linear' or 'log' interpolation method * Reference: Gabrielsson J, Weiner D. Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications. 5th ed. 2016. (ISBN:9198299107). 5) Added handling of steady-state profile NCA

Getting started

Package details

AuthorKyun-Seop Bae [cre,aut,cph] Henning Schmidt [cre,aut]
MaintainerHenning Schmidt <henning.schmidt@intiquan.com>
LicenseGPL-3
Version0.5.0
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("IntiQuan/NonCompartIQR")
IntiQuan/NonCompartIQR documentation built on Nov. 8, 2019, 2:29 a.m.