IMR90: IMR90 data, a Human lung fibroblast cell line.

Description Usage Format Value References Examples

Description

Data used in the batch effect correction paper of Johnson, Li and Rabinovich. The data are from a cell-line experimental designed to reveal whether exposing mammalian cells to nitric oxide (NO) stabilizes mRNAs. The data comprises one treatment, one control and 2 time points (0 h and 7.5 h), resulting in 4 distinct (2 treatment x 2 time points) experimental conditions. There were 3 batches and a total of 12 samples, with each batch consisting of 1 replicate from each of the experimental conditions. Affymetrix HG-U133A Arrays were normalised and background adjusted as a whole using the RMA procedure in MATLAB.

Usage

1

Format

Two data frames. imr90.data has 22,223 probesets (rows) and 12 samples (columns). While imr90.info is a description of the samples, with two columns:

Treatment

the treatment applied to the cells

Batch

batch processing number

Value

promise

References

Johnson et al. Biostatistics (2007). doi: 10.1093/biostatistics/kxj037

Examples

1

JasonR055/HarmanData documentation built on May 7, 2019, 10:32 a.m.