Description Usage Format Value References Examples
Data used in the batch effect correction paper of Johnson, Li and Rabinovich. The data are from a cell-line experimental designed to reveal whether exposing mammalian cells to nitric oxide (NO) stabilizes mRNAs. The data comprises one treatment, one control and 2 time points (0 h and 7.5 h), resulting in 4 distinct (2 treatment x 2 time points) experimental conditions. There were 3 batches and a total of 12 samples, with each batch consisting of 1 replicate from each of the experimental conditions. Affymetrix HG-U133A Arrays were normalised and background adjusted as a whole using the RMA procedure in MATLAB.
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Two data frames. imr90.data
has 22,223 probesets (rows) and 12
samples (columns). While imr90.info
is a description of the samples,
with two columns:
Treatment
the treatment applied to the cells
Batch
batch processing number
promise
Johnson et al. Biostatistics (2007). doi: 10.1093/biostatistics/kxj037
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