Description Usage Arguments Value
View source: R/EMM_functions_cpp.R
Calculte -log10(p) by score test (slow, for general cases)
1 | score.cpp(y, Gs, Gu, Ge, P0, chi0.mixture = 0.5)
|
y |
A n \times 1 vector. A vector of phenotypic values should be used. NA is allowed. |
Gs |
A list of kernel matrices you want to test. For example, Gs = list(A.part = K.A.part, D.part = K.D.part) |
Gu |
A n \times n matrix. You should assign ZKZ', where K is covariance (relationship) matrix and Z is its design matrix. |
Ge |
A n \times n matrix. You should assign identity matrix I (diag(n)). |
P0 |
A n \times n matrix. The Moore-Penrose generalized inverse of SV0S, where S = X(X'X)^{-1}X' and V0 = σ^2_u Gu + σ^2_e Ge. σ^2_u and σ^2_e are estimators of the null model. |
chi0.mixture |
RAINBOW assumes the test statistic l1' F l1 is considered to follow a x chisq(df = 0) + (1 - a) x chisq(df = r). where l1 is the first derivative of the log-likelihood and F is the Fisher information. And r is the degree of freedom. The argument chi0.mixture is a (0 <= a < 1), and default is 0.5. |
-log10(p) calculated by score test
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